Wrinkles
Rhytid
Wrinkles are creases in the skin. The medical term for wrinkles is rhytids.

The skin is the largest organ of the body. The skin and its derivatives (hair, nails, sweat and oil glands) make up the integumentary system. One of the main functions of the skin is protection. It protects the body from external factors such as bacteria, chemicals, and temperature. The skin contains secretions that can kill bacteria and the pigment melanin provides a chemical pigment defense against ultraviolet light that can damage skin cells. Another important function of the skin is body temperature regulation. When the skin is exposed to a cold temperature, the blood vessels in the dermis constrict. This allows the blood which is warm, to bypass the skin. The skin then becomes the temperature of the cold it is exposed to. Body heat is conserved since the blood vessels are not diverting heat to the skin anymore. Among its many functions the skin is an incredible organ always protecting the body from external agents.

Sagging or wrinkled skin occurs naturally with increasing age. Folds and fat deposits appear around the neck, and deep flexion creases form between the nose and mouth. The jawline grows jowly and slack. Heredity, poor diet, smoking, or obesity may contribute to early or severe skin problems. A facelift can help repair some of the visible damage to skin, fat, and muscles and can restore a younger look. A facelift can be done alone or with nose reshaping, a forehead lift, or eyelid surgery.
Considerations
Most wrinkles come from aging changes in skin. Aging of the skin, hair and nails is a natural process. There is little you can do to slow the rate of skin aging, but many things in the environment will speed it up.
Frequent exposure to sunlight results in early skin wrinkles and dark areas (liver spots). It also increases the chances of getting skin cancer. Exposure to cigarette smoke can also make the skin wrinkle sooner.
Causes
Common causes of wrinkles include:
- Genetic factors (family history)
- Normal aging changes in the skin
- Smoking
- Sun exposure
Home Care
Stay out of the sun as much as possible to limit skin wrinkles. Wear hats and clothing that protect your skin and use sunscreen daily. Avoid smoking and secondhand smoke.
When to Contact a Medical Professional
Wrinkles are not usually a cause for concern unless they occur at an early age. Talk to your health care provider if you think that your skin is getting wrinkled faster than normal for someone your age. You may need to see a skin specialist (dermatologist) or a plastic surgeon.
What to Expect at Your Office Visit
Your provider will ask questions, such as:
- When did you first notice that your skin seemed more wrinkled than normal?
- Has it changed in any way?
- Has a skin spot become painful or does it bleed?
- What other symptoms are you having?
Your provider will examine your skin. You may need a skin lesion biopsy if you have any abnormal growths or skin changes.
These are some treatments for wrinkles:
- Tretinoin (Retin-A) or creams containing alpha-hydroxy acids (such as glycolic acid)
- Chemical peels, laser resurfacing, or dermabrasion work well for early wrinkles
- Botulinum toxin (Botox) may be used to correct some of the wrinkles that are caused by overactive facial muscles
- Medicines injected under the skin can fill in wrinkles or stimulate collagen production
- Plastic surgery for age-related wrinkles (for example, a facelift)
References
Baumann L, Weisberg E. Skincare and nonsurgical skin rejuvenation. In: Peter RJ, Neligan PC, eds. Plastic Surgery, Volume 2: Aesthetic Surgery. 4th ed. Philadelphia, PA: Elsevier; 2018:chap 4.
Patterson JW. Disorders of elastic tissue. In: Patterson JW, ed. Weedon's Skin Pathology. 4th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2016:chap 12.
Version Info
Last reviewed on: 10/14/2018
Reviewed by: Michael Lehrer, MD, Clinical Associate Professor, Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
