A gumma is a soft, tumor-like growth of the tissues (granuloma) that occurs in people with syphilis.
A gumma is caused by the bacteria that cause syphilis. It appears during late-stage tertiary syphilis. It most often contains a mass of dead and swollen fiber-like tissue. It is most often seen in the liver. It also can occur in the:
Similar-looking sores sometimes occur with tuberculosis.
Centers for Disease Control and Prevention website. Sexually transmitted infections treatment guidelines, 2021.
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Last reviewed on: 7/13/2021
Reviewed by: John D. Jacobson, MD, Department of Obstetrics and Gynecology, Loma Linda University School of Medicine, Loma Linda, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.