Navneet Dogra, PhD Email Navneet Dogra
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- Positions
- ASSISTANT PROFESSOR | Genetics and Genomic Sciences
- ASSISTANT PROFESSOR | Pathology, Molecular and Cell Based Medicine
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- Language
- English
Dr. Dogra's laboratory is working on the emerging field of genomics, liquid biopsy, and gene delivery, including: 1) Exosomes, Extracellular vesicles – nanoparticles actively secreted by cancer / tumor and benign tissue in human biofluids, 2) Cell-free DNA, RNA, and proteins – non-invasive tools for monitoring real time disease state, through RNA Sequencing, qRT-PCR, Proteomics etc., 3) Bioengineering – intersection of nanotechnology, microfluidics, drug delivery, and bioinformatics, and 4) Virus - Adeno-Associated Virus (AAV), SARS-CoV-2/COVID-19 genomics, drug discovery, and fundamental mechanism of endocytosis.
Prior to Mount Sinai, Dr. Dogra led research efforts at IBM research and Yale University to drive translational research in “liquid biopsy in cancer” and “drug delivery” by bridging together clinical and experimental oncology and develop novel tools for biosensing of genetic markers.
Dr. Dogra has recently filed for two US patents relating to “exosomes nanoparticles assisted drug delivery” and “tumor heterogeneity”. He has published in a diverse array of journals including Cell (research featured on the cover), Lab-on-a-chip, ACS Applied Materials and Interfaces (cover feature), ACS Bioconjugate Chemistry, Langmuir (cover feature), and Scientific Reports.
Media Coverage:
Dr. Dogra’s research has been featured in multiple media outlets including Yale News, NBC News, Yale Engineering Magazine, Science Daily, Futurity, R&D Magazine, Fox News, and Wall Street Journal...
Awards:
2020 Mount Sinai Alzheimer's Disease Research Center (ADRC) Scholar.
IBM “5 in 5” groundbreaking research award, Watson Research Center, NY
IBM Outstanding Technical Achievement Award, Watson Research Center, NY
Yale University Young Global Scholars Program, Falling Walls Finalist, New Haven, CT
Oak Ridge National Lab, TN, Summer Fellowship
Gower Research Fellow (Outstanding graduate student award), SIU, Carbondale IL
Dissertation research award, Southern Illinois University Carbondale, IL
Lab website:
https://labs.icahn.mssm.edu/dogralab/
Full list of publications :
https://scholar.google.com/citations?user=V4Was6cAAAAJ&hl=en&oi=ao
Research Topics
Anti-Tumor Therapy, Biochemistry, Biomedical Informatics, Biomedical Sciences, Blood-Brain Barrier, Brain, Cancer, Cancer Genetics, Cell Biology, Clinical Genomics, Gene Discovery, Gene Expressions, Gene Therapy, Genetics, Genomics, Imaging, Membranes, Nanotechnology, Oncogenes, Parkinson's Disease, Pathology, Prostate, Protein Trafficking & Sorting, RNA, RNA Transport & Localization, Signal Transduction, Spectroscopy, Tissue Engineering, Trafficking, Tumor Suppressor Genes, Tumorigenesis, Viruses and Virology
Multi-Disciplinary Training Areas
Cancer Biology [CAB], Genetics and Genomic Sciences [GGS], Neuroscience [NEU], Pharmacology and Therapeutics Discovery [PTD]
Education
Bachelor's of Science, Himachal Pradesh University
Doctorate, Southern Illinois University Carbondale
Master's of Science, Guru Nanak Dev University
Post Doctoral Fellow, IBM Watson Research Center
Post Doctoral Fellow, Yale University
Language
English
2020
Mount Sinai Alzheimer's Disease Research Center (ADRC) Scholar.
Icahn School of Medicine at Mount Sinai Hospital
2019
Outstanding Technical Achievement Award
IBM Watson Research Center
2016
“5 in 5” groundbreaking research award
IBM Watson Research Center
Five ground-breaking scientific innovations with the potential to change the way people live, work and interact over the next five years.
2015
Yale Young Global Scholars Program, Falling Walls Finalist
Yale University
interdisciplinary research for young academics
2013
Dissertation research award
Graduate School
2013
Gower Research Fellow
Graduate School
Drug and Gene Delivery
Exosomes and nanoparticles for drug delivery.
Exosomes and other Extracellular Vesicles
nanovesicles used for diagnostics, therapy, and bioengineering
Liquid-Biopsy in Cancer
Can we detect cancer biomarkers present in bodily fluids and avoid unnecessary surgical procedures? To answer this question, my research is focused on developing new liquid biopsy methods using circulating exosomes and extracellular vesicles, microfluidics, and next-gen genomic technologies.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr.Dogra did not report having any of the following types of financial relationships with industry during 2020 and/or 2021: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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