Hanna Y Irie, MD, PhD
- ASSOCIATE PROFESSOR | Medicine, Hematology and Medical Oncology
- ASSOCIATE PROFESSOR | Oncological Sciences
- Cancer (Oncology)
- Hospital Affiliation
- The Mount Sinai Hospital
- Dubin Breast Center 212-241-3300 212-241-3300
I am a medical oncologist specializing in the care of patients with breast cancer. As a physician-scientist, I also lead a research laboratory that is focused on developing targeted therapies tailored for specific breast cancer subtypes and for individual patients. I have a particular interest in better understanding triple negative breast cancers, with the goal of integrating genetic analysis to the development of improved treatments for our patients.
I am co-PI of the Breast Tumor Biospecimen Repository, which is a bank of patient breast tumors; analysis of these tumors will provide insights into the genetic changes that determine sensitivity to specific targeted therapies for breast cancer. I am also co-PI of a study investigating the use of patient-derived xenograft models as a model for chemotherapy treatment sensitivity for patients with triple negative breast cancers; if successful, these models may be used in the future to help us better tailor treatments for individual patients. My research laboratory has identified several new candidate therapeutic targets for Her2+ and triple negative breast cancers resistant to current treatments, and we are working to translate our findings to clinical studies and trials.
I am a member of the American Society of Clinical Oncology and the American Association for Cancer Research.
Anti-Tumor Therapy, Cancer, Cell Biology, Cell Transformation, Growth Factors and Receptors, Protein Kinases
MD,PHD, Harvard Medical School
BA, Harvard University
Clinical Fellow, Dana-Farber Cancer Institute
Instructor, Dana-Farber Cancer Institute/Harvard Medical School
Intern/Resident, Massachusetts General Hospital
MD, Harvard Medical School
PhD, Harvard Medical School
Research Fellow, Harvard Medical School
Residency, Internal Medicine
Massachusetts General Hospital
Dana Farber Cancer Institute
Breast Cancer Alliance Exceptional Project Grant
Breast Cancer Alliance
Breast Cancer Research Foundation Grant
Breast Cancer Research Foundation
AACR-Genentech BioOncology Career Development Award for Research on the Her Family in Cancer
Susan G Komen Career Catalyst Award
Susan G Komen for the Cure
Dana Farber Cancer Institute SPORE in Breast Cancer Career Development Award
Terri Brodeur Breast Cancer Research Foundation Grant
Terri Brodeur Breast Cancer Research Foundation
AACR Scholar-in-Training Award
American Assocaition for Cancer Research
K08 Mentored Clinical Scientist Award
ASCO Young Investigator Award
American Society for Clinical Oncology
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr.Irie did not report having any of the following types of financial relationships with industry during 2020 and/or 2021: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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