- PROFESSOR Medicine, Cardiology
- Director, Cardiac Arrhythmia Service
- The Leona M. and Harry B. Helmsley Charitable Trust Professor of Medicine in Cardiac Electrophysiology
The Leona M. and Harry B. Helmsley Charitable Trust Professor of Medicine in Cardiac Electrophysiology
Endowed Professorship: The Leona M. and Harry B. Helmsley Charitable Trust Professor of Medicine in Cardiac Electrophysiology
Best Doctors in Boston
Center for Minimally Invasive Therapy
Howard Hughes Medical Institute Scholarship
Alpha Omega Alpha Medical Society
ResearchCatheter Ablation of Atrial Fibrillation (AF)
AF is the most common heart arrhythmia. Medications are only modestly effective, so we are working on catheter-based approaches to treat AF by directly cauterizing the tissue causing the problem. We are working with other approaches to do this catheter ablation procedure using laser energy or cryo energy (freezing tissue).
Left Atrial Appendage Closure
People with AF are at high risk for stroke-thus most people receive Warfarin Rx. We are working on approaches to use catheters to close the left atrial appendage. Then, patients would be protected from stroke without having to take Warfarin (Coumadin).
Catheter Ablation of Ventricular Tachycardia (VT)
Ventricular tachycardias are the most common cause of sudden death. The standard approach is to place defibrillators (ICDs) in patients at high risk for sudden death. We are working on approaches to use catheters to cauterize (ablate) the tissue responsible for these arrhythmias.
Reddy VY, Neuzil P, Taborsky M, Ruskin JN. Short-term results of substrate mapping and radiofrequency ablation of ischemic ventricular tachycardia using a saline-irrigated catheter. J Am Coll Cardiol 2003 Jun; 41(12): 2228-2236.
D'Avila A, Scanavacca M, Sosa E, Ruskin JN, Reddy VY. Pericardial anatomy for the interventional electrophysiologist. J Cardiovasc Electrophysiol 2003 Apr; 14(4): 422-430.
Reddy VY, Malchano ZJ, Holmvang G, Schmidt EJ, d'Avila A, Houghtaling C, Chan RC, Ruskin JN. Integration of cardiac magnetic resonance imaging with three-dimensional electroanatomic mapping to guide left ventricular catheter manipulation: feasibility in a porcine model of healed myocardial infarction. J Am Coll Cardiol 2004 Dec 7; 44(11): 2202-2213.
Mikaelian BJ, Malchano ZJ, Neuzil P, Weichet J, Doshi SK, Ruskin JN, Reddy VY. Images in cardiovascular medicine. Integration of 3-dimensional cardiac computed tomography images with real-time electroanatomic mapping to guide catheter ablation of atrial fibrillation. Circulation 2005 Jul; 112(2): e35-36.
Obel OA, d'Avila A, Neuzil P, Saad EB, Ruskin JN, Reddy VY. Ablation of left ventricular epicardial outflow tract tachycardia from the distal great cardiac vein. J Am Coll Cardiol 2006 Nov 7; 48(9): 1813-1817.
Aryana A, d'Avila A, Heist EK, Mela T, Singh JP, Ruskin JN, Reddy VY. Remote magnetic navigation to guide endocardial and epicardial catheter mapping of scar-related ventricular tachycardia. Circulation 2007 Mar 13; 115(10): 1191-1200.
Reddy VY, Neuzil P, Malchano ZJ, Vijaykumar R, Cury R, Abbara S, Weichet J, McPherson CD, Ruskin JN. View-synchronized robotic image-guided therapy for atrial fibrillation ablation: experimental validation and clinical feasibility. Circulation 2007 May 29; 115(21): 2705-2714.
Reddy VY, Reynolds MR, Neuzil P, Richardson AW, Taborsky M, Jongnarangsin K, Kralovec S, Sediva L, Ruskin JN, Josephson ME. Prophylactic catheter ablation for the prevention of defibrillator therapy. N Engl J Med 2007 Dec; 357(26): 2657-2665.
Dukkipati SR, Mallozzi R, Schmidt EJ, Holmvang G, d'Avila A, Guhde R, Darrow RD, Slavin G, Fung M, Malchano Z, Kampa G, Dando JD, McPherson C, Foo TK, Ruskin JN, Dumoulin CL, Reddy VY. Electroanatomic mapping of the left ventricle in a porcine model of chronic myocardial infarction with magnetic resonance-based catheter tracking. Circulation 2008 Aug 19; 118(8): 853-862.
Reddy VY. Atrial fibrillation: unanswered questions and future directions. Cardiol Clin 2009 Feb; 27(1): 201-216, x-xi.
Reddy VY, Neuzil P, Themistoclakis S, Danik SB, Bonso A, Rossillo A, Raviele A, Schweikert R, Ernst S, Kuck KH, Natale A. Visually-guided balloon catheter ablation of atrial fibrillation: experimental feasibility and first-in-human multicenter clinical outcome. Circulation 2009 Jul 7; 120(1): 12-20.
Ahmed H, Reddy VY. Technical advances in the ablation of atrial fibrillation. Heart Rhythm; In Press.
Holmes DR, Reddy VY, Turi ZG, Doshi SK, Sievert H, Buchbinder M, Mullin CM, Sick P, P. Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet 2009 Aug 15; 374(9689): 534-542.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Reddy during 2012 and/or 2013. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
- ABIOMED, Inc.; Biosense Webster; CardioFocus; Cibiem, Inc.; Coherex Medical; Endosense; GDS, Inc.; Keystone Heart Ltd.; Medtronic CryoCath LP; St. Jude Medical, Inc.; Voyage Medical, Inc.
Scientific Advisory Board:
- Boston Scientific Corporation; CardioInsight Technologies Inc.
Industry-Sponsored Lectures: MSSM faculty occasionally give lectures at events sponsored by industry, but only if the events are free of any marketing purpose.
- BIOTRONIK; Biosense Webster; Boston Scientific Corporation; CardioFocus; Medtronic CryoCath LP; St. Jude Medical, Inc.
- St. Jude Medical, Inc.
Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)
- Sound Interventions
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.
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