Photo of Steven Burakoff

Steven Burakoff

  • PROFESSOR Oncological Sciences
  • PROFESSOR Medicine, Hematology and Medical Oncology
Print ProfilePrint Profile



  • American Board of Internal Medicine

Research Topics


  • MD, Albany Medical College

  • Rockefeller University

  • MA, Queens College

  • Harvard Medical School

  • MA (hon.), Harvard University

  • New York Hospital-Cornell Medical Center

  • Internship, General Medicine
    Cornell Medical Center

  • Residency, General Medicine
    Cornell Medical Center

  • Fellowship, Immunology
    Rockefeller University



  • 2009 -
    Lifetime Achievement Award
    American Association of Immunologists

  • 2006 -
    Lynne Cohen Foundation Awardee

  • 2003 -
    Distinguished Alumnus 2003

  • 2002 -
    Theobold Smith Alumni Lecture
    Albany Medical College

  • 2001 -
    ISI Highly Cited Researcher (1980-2000)

  • 2000 -
    Laura and Isaac Perlmutter Professor
    New York University, School of Medicine

  • 1998 -
    Margaret M. Dyson Professor of Pediatrics
    Harvard Medical School

  • 1995 -
    Ted Williams Senior Investigator
    Dana-Farber Cancer Institute

  • 1995 -
    Association of American Physicians

  • 1994 -
    Horizons in Biomedical Research Lecture
    Cleveland Clinic Foundation

  • 1992 -
    David A. Talmadge Lecture
    Colorado Allergy Society


Major Research Interests:

   1. Cellular and molecular immunology;
   2. T cell activation and signal transduction;
   3. Transplantation immunology.


Jin YJ, Cai CY, Zhang X, Zhang HT, Burakoff SJ. Lysine144, a Ubiquitin Attachment Site in HIV-1 Nef, Is Required for Nef-mediated CD4 Downregulation. J Immunol 2008;.

Sawasdikosol S, Pyarajan S, Alzabin S, Matejovic G, Burakoff SJ. Prostaglandin E2 activates HPK1 activity via a PKA-dependent pathway. J Biol Chem 2007 Nov; 282: 34693-34699.

Mathews JP, Taylor BS, Bader GD, Pyarajan S, Antoniotti M, Chinnaiyan AM, Sander C, Burakoff SJ, Mishra B. From bytes to bedside: data integration and computational biologyfor translational cancer research. PLoS Comput Biol 2007 Feb 23; 3(2): e12.

Fragoso R, Pyarajan S, Irie HY, Burakoff SJ. CD8/Lck transgene is able to drive thymocyte differentiation. J. Immun 2006 Feb 15; 176(4): 2669.

Jin JJ, Yi Cai C, Zhang X, Zhang HT, Hirst JA, Burakoff SJ. HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent. J. Immun 2006 Feb 15; 176(4): 2669.

Zambricki E, Shigeoka A, Kishimoto H, Sprent J, Burakoff S, Carpenter C, Milford E, McKay D. Signaling T cell survival and death by IL-2 and IL-15. Am J Transplant 2005; 11: 2623-2631.

Su MW, Pyarajan S, Chang JH, Yu CL, Jin YJ, Stierhof YD, Walden P, Burakoff SJ. Fratricide of CD8+ cytotoxic T Lymphocytes is dependent on cellular activation and perforin-mediated killing. Eur J Immunol 2004; 34: 2459-2470.

Frazer-Abel AA, Baksh S, Fosmire SP, Willis D, Pierce AM, Meylemans H, Linthicum DS, Burakoff SJ, Coons T, Bellgrau D. Nicotine activates NFATc2 and prevents cell cycle entry in T cells. J Pharmacol Exp Ther 2004; 311: 758-769.

Friedman JS, Alpdogan O, van den Brink MR, Liu C, Hurwiz D, Boyd A, Kupper TS, Burakoff SJ. Increasing T cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex-mismatched bone marrow transplant model. Biol Blood Marrow Transplant 2004; 10: 448-460.

Friedman JS, Lopez MF, Fleming MD, Rivera A, Martin FM, Welsh ML, Boyd AS, Doctrow SR, Burakoff SJ. SOD2 Deficiently anemia: protein oxidation and altered protein expression reveal targets of damage, stress response and anti -oxidant responsiveness. Blood 2004; 104: 2565-2573.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Burakoff during 2015 and/or 2016. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Scientific Advisory Board:

  • Cold Spring Harbor Laboratory (CSHL)

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.

Insurance Information

Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).

Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.

Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.

Edit profile in Sinai Central


One Gustave L. Levy Place
Box 1128
New York, NY 10029

Tel: 212-659-8959
Fax: 212-241-9244


Icahn (East) Building Floor 1st fl- Suite 100 Room L1-15C
1425 Madison Avenue
New York, NY 10029