BA, University of Chicago
PhD, Princeton University
Biophysics and Systems Pharmacology [BSP], Cancer Biology [CAB], Design Technology and Entrepreneurship [DTE], Developmental and Stem Cell Biology [DSCB], Genetics and Genomic Sciences [GGS], Neuroscience [NEU]
Levine BD, Cagan RL. Drosophila Lung Cancer Models Identify Trametinib plus Statin as Candidate Therapeutic. Cell reports 2016 Jan;.
Hackett R, Moulton OC, Cagan RL. A new brand for Disease Models & Mechanisms and The Company of Biologists. Disease models & mechanisms 2015 Dec; 8(12).
Hirabayashi S, Cagan RL. Salt-inducible kinases mediate nutrient-sensing to link dietary sugar and tumorigenesis in Drosophila. eLife 2015 Nov; 4.
Na J, Sweetwyne MT, Park AS, Susztak K, Cagan RL. Diet-Induced Podocyte Dysfunction in Drosophila and Mammals. Cell reports 2015 Jul;.
Hirabayashi S, Baranski TJ, Cagan RL. Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling. Cell 2013 Aug; 154(3).
Dar A, Das T, Shokat K, Cagan R. Chemical Genetic Discovery of Targets and Anti-targets for Cancer Therapy. Nature 2012; 486(7401).
Johnson R, Sedgwick A, D’Souza-Schorey C, Cagan R. Role for a Cindr-Arf6 axis in patterning emerging epithelia. Mol. Biol. Cell 2011;(22(23)): 4513-4526.
Vidal M, Salavaggione L, Ylagan L, Wilkins M, Watson M, Weilbaecher K, Cagan R. A Role for the Epithelial Microenvironment at Tumor Boundaries: Evidence from Drosophila and Human Squamous Cell Carcinomas. Am J Pathol 2010; 176(6): 3007-3014.
Cordero J, Macagno J, Stefanatos R, Strathdee K, Cagan R, Vidal M. Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter. Dev Cell 2010; 15(18(6)): 999-1011.
Vidal M, Warner S, Read R, Cagan R. Differing Src signaling levels have distinct outcomes in Drosophila. Cancer Research 2007; 67(21): 10278-10285.
Vidal M, Larson D, Read R, Cagan R. Drosophila Csk regulates oncogenic growth through multiple mechanisms. Developmental Cell 2006; 10(1): 33-44.
Vidal M, Wells S, Ryan A, Cagan R. ZD6474 supresses oncogenic Ret isoforms in a Drosophila model for Type 2 Multiple > Endocrine Neoplasia Syndromes and Papillary Thyroid Carcinoma . Cancer Research 2005; 65(9): 3538-3541.
Bao S, Cagan R. Preferential Adhesion mediated by Hibris and Roughest Regulates Morphogenesis and Patterning in the Drosophila Eye . Developmental Cell 2005; 8(6): 925-935.
Read R, Goodfellow P, Mardis E, Novack N, Cagan R. A Drosophila model of Multiple Endocrine Neoplasia Type 2. Genetics 2005; 171: 1057-1081.
Read R, Bach E, Cagan R. Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways . Mol Cell Biol 2004; 24(15): 6676-6689.
Hays R, Wickline L, Cagan R. Degradation of a Drosophila IAP by the morgue ubiquitin conjugase. Nature Cell Biology 2002; 6: 425-431.
Powell P, Wesley C, Spencer S, Cagan R. Scabrous mediates long-range signaling by Notch. Nature 2000; 409: 626-630.
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Dr.Cagan did not report having any of the following types of financial relationships with industry during 2015 and/or 2016: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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