Biostatistics, Genetics, Mathematical and Computational Biology
Multi-Disciplinary Training Area
Genetics and Genomic Sciences [GGS]
Schadt EE, Woo S, Hao K. Bayesian method to predict individual SNP genotypes from gene expression data. Nature genetics 2012 May; 44(5).
Hao K, Bossé Y, Nickle DC, Paré PD, Postma DS, Laviolette M, Sandford A, Hackett TL, Daley D, Hogg JC, Elliott WM, Couture C, Lamontagne M, Brandsma CA, van den Berge M, Koppelman G, Reicin AS, Nicholson DW, Malkov V, Derry JM, Suver C, Tsou JA, Kulkarni A, Zhang C, Vessey R, Opiteck GJ, Curtis SP, Timens W, Sin DD. Lung eQTLs to help reveal the molecular underpinnings of asthma. PLoS genetics 2012 Dec; 8(11).
Hong X, Hao K, Ladd-Acosta C, Hansen KD, Tsai HJ, Liu X, Xu X, Thornton TA, Caruso D, Keet CA, Sun Y, Wang G, Luo W, Kumar R, Fuleihan R, Singh AM, Kim JS, Story RE, Gupta RS, Gao P, Chen Z, Walker SO, Bartell TR, Beaty TH, Fallin MD, Schleimer R, Holt PG, Nadeau KC, Wood RA, Pongracic JA, Weeks DE, Wang X. Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Nature communications 2015 Feb; 6.
Morissette MC, Gao Y, Shen P, Thayaparan D, Bérubé JC, Paré PD, Brandsma CA, Hao K, Bossé Y, Ettinger R, Herbst R, Humbles AA, Kolbeck R, Zhong N, Chen R, Stämpfli MR. Role of BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice. Physiological reports 2016 Dec; 4(24).
Luo W, Obeidat M, Di Narzo AF, Chen R, Sin DD, Paré PD, Hao K. Airway Epithelial Expression Quantitative Trait Loci Reveal Genes Underlying Asthma and Other Airway Diseases. American journal of respiratory cell and molecular biology 2016 Feb; 54(2).
Moeini A, Sia D, Zhang Z, Camprecios G, Stueck A, Dong H, Montal R, Torrens L, Martinez-Quetglas I, Fiel MI, Hao K, Villanueva A, Thung SN, Schwartz ME, Llovet JM. Mixed hepatocellular cholangiocarcinoma tumors: Cholangiolocellular carcinoma is a distinct molecular entity. Journal of hepatology 2017 May; 66(5).
Hong X, Hao K, Ji H, Peng S, Sherwood B, Di Narzo A, Tsai HJ, Liu X, Burd I, Wang G, Ji Y, Caruso D, Mao G, Bartell TR, Zhang Z, Pearson C, Heffner L, Cerda S, Beaty TH, Fallin MD, Lee-Parritz A, Zuckerman B, Weeks DE, Wang X. Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth. Nature communications 2017 Jun; 8.
Pasinetti GM, Ho L, Cheng H, Wang J, Simon JE, Wu QL, Zhao D, Carry E, Ferruzzi MG, Faith J, Valcarcel B, Hao K. A comprehensive database and analysis framework to incorporate multiscale data types and enable integrated analysis of bioactive polyphenols. Molecular pharmaceutics 2017 Jun;.
Deyssenroth MA, Peng S, Hao K, Lambertini L, Marsit CJ, Chen J. Whole-transcriptome analysis delineates the human placenta gene network and its associations with fetal growth. BMC genomics 2017 Jul; 18(1).
Huang KL, Marcora E, Pimenova AA, Di Narzo AF, Kapoor M, Jin SC, Harari O, Bertelsen S, Fairfax BP, Czajkowski J, Chouraki V, Grenier-Boley B, Bellenguez C, Deming Y, McKenzie A, Raj T, Renton AE, Budde J, Smith A, Fitzpatrick A, Bis JC, DeStefano A, Adams HH, Ikram MA, van der Lee S, Del-Aguila JL, Fernandez MV, Ibañez L, Sims R, Escott-Price V, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Lambert JC, van Duijn C, Launer L, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Zhang B, Borecki I, Kauwe JS, Cruchaga C, Hao K, Goate AM. A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease. Nature neuroscience 2017 Aug; 20(8).
Li H, Cai J, Chen R, Zhao Z, Ying Z, Wang L, Chen J, Hao K, Kinney PL, Chen H, Kan H. Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification. Circulation 2017 Aug; 136(7).
Torrecilla S, Sia D, Harrington AN, Zhang Z, Cabellos L, Cornella H, Moeini A, Camprecios G, Leow WQ, Fiel MI, Hao K, Bassaganyas L, Mahajan M, Thung SN, Villanueva A, Florman S, Schwartz ME, Llovet JM. Trunk events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma. Journal of hepatology 2017 Aug;.
Zhang Z, Hao K, Ross MJ, Murphy B, Menon MC. APOL1 G2 risk allele-clarifying nomenclature. Kidney international 2017 Aug; 92(2).
Ma Y, Hao L, Ke H, Liang Z, Ma J, Liu Z, Li Y. LuxS/AI-2 in Streptococcus agalactiae reveals a key role in acid tolerance and virulence. Research in veterinary science 2017 Aug; 115.
Wang L, Hao K, Yang T, Wang C. Role of the Lung Microbiome in the Pathogenesis of Chronic Obstructive Pulmonary Disease. Chinese medical journal 2017 Sep; 130(17).
Peng S, Deyssenroth MA, Di Narzo AF, Lambertini L, Marsit CJ, Chen J, Hao K. Expression quantitative trait loci (eQTLs) in human placentas suggest developmental origins of complex diseases. Human molecular genetics 2017 Sep; 26(17).
Wang L, Ke H, Ma J, Liu J. Investigation of the 'double cross' splitting mechanism of single-crystal diamond under nanoindentation via molecular dynamics simulation. Journal of molecular modeling 2017 Sep; 23(10).
Wang Z, Ying YM, Li KQ, Zhang Y, Chen BY, Zeng JJ, He XJ, Jiang MM, Chen BX, Wang Y, Xu XD, Hao K, Zhu MH, Zhang W. Marsdeniae tenacissima extract-induced growth inhibition and apoptosis in hepatoma carcinoma cells is mediated through the p53/nuclear factor-κB signaling pathway. Experimental and therapeutic medicine 2017 Sep; 14(3).
Everson TM, Kappil M, Hao K, Jackson BP, Punshon T, Karagas MR, Chen J, Marsit CJ. Maternal exposure to selenium and cadmium, fetal growth, and placental expression of steroidogenic and apoptotic genes. Environmental research 2017 Oct; 158.
Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE. A functional genomics predictive network model identifies regulators of inflammatory bowel disease. Nature genetics 2017 Oct; 49(10).
Boorsma CE, van der Veen TA, Putri KS, de Almeida A, Draijer C, Mauad T, Fejer G, Brandsma CA, van den Berge M, Bossé Y, Sin D, Hao K, Reithmeier A, Andersson G, Olinga P, Timens W, Casini A, Melgert BN. A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages. Scientific reports 2017 Oct; 7(1).
Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, Miller BE, Rennard S, Spira A, Hackett TL, Lam W, Lam S, Faner R, Agusti A, Hogg JC, Sin DD, Paré PD. Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers. American journal of respiratory cell and molecular biology 2017 Oct; 57(4).
Obeidat M, Li X, Burgess S, Zhou G, Fishbane N, Hansel NN, Bossé Y, Joubert P, Hao K, Nickle DC, van den Berge M, Timens W, Cho MH, Hobbs BD, de Jong K, Boezen M, Hung RJ, Rafaels N, Mathias R, Ruczinski I, Beaty TH, Barnes KC, Paré PD, Sin DD. Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation. The European respiratory journal 2017 Nov; 50(5).
Wang L, Ma J, He X, Ke H, Liu J, Zhang C. Learning the deformation mechanism of poly(vinylidine fluoride-co-chlorotrifluoroethylene): an insight into strain-induced microstructure evolution via molecular dynamics. Journal of molecular modeling 2017 Nov; 23(12).
Zhang J, Peng S, Cheng H, Nomura Y, Di Narzo AF, Hao K. Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes. Scientific reports 2017 Dec; 7(1).
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Dr. Hao has not yet completed reporting of Industry relationships.
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