BAS, Stanford University
MD, Weill Medical College of Cornell University
PhD, The Rockefeller University
, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
Biophysics and Systems Pharmacology [BSP], Immunology [IMM], Microbiology [MIC]
Avant Garde Award in HIV/AIDS research
National Institute of Drug Abuse, NIH
Irma T. Hirschl Monique Weill-Caulier Career Scientist Award
Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Diseases
National Research Service Award, National Institute for Allergy and Infectious Disease
National Institutes of Health
Graduation with Honors in Biological Sciences
Graduation with Distinction in Philosophy
Swartz TH, Esposito AM, Durham ND, Hartmann BM, Chen BK. P2X-Selective Purinergic Antagonists Are Strong Inhibitors of HIV-1 Fusion during both Cell-to-Cell and Cell-Free Infection. Journal of virology 2014 Oct; 88(19).
Alvarez RA, Hamlin RE, Monroe A, Moldt B, Hotta MT, Rodriguez Caprio G, Fierer DS, Simon V, Chen BK. HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells. Journal of virology 2014 Jun; 88(11).
Durham ND, Yewdall AW, Chen P, Lee R, Zony C, Robinson JE, Chen BK. Neutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail. Journal of virology 2012 Jul; 86(14).
Dale BM, McNerney GP, Thompson DL, Hubner W, de Los Reyes K, Chuang FY, Huser T, Chen BK. Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusion. Cell host & microbe 2011 Dec; 10(6).
Del Portillo A, Tripodi J, Najfeld V, Wodarz D, Levy DN, Chen BK. Multiploid inheritance of HIV-1 during cell-to-cell infection. Journal of virology 2011 Jul; 85(14).
Chen P, Chen BK, Mosoian A, Hays T, Ross MJ, Klotman PE, Klotman ME. Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. Journal of the American Society of Nephrology : JASN 2011 Mar; 22(3).
Hübner W, McNerney GP, Chen P, Dale BM, Gordon RE, Chuang FY, Li XD, Asmuth DM, Huser T, Chen BK. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (New York, N.Y.) 2009 Mar; 323(5922).
Hübner W, Chen P, Del Portillo A, Liu Y, Gordon RE, Chen BK. Sequence of human immunodeficiency virus type 1 (HIV-1) Gag localization and oligomerization monitored with live confocal imaging of a replication-competent, fluorescently tagged HIV-1. Journal of virology 2007 Nov; 81(22).
Chen P, Hübner W, Spinelli MA, Chen BK. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. Journal of virology 2007 Nov; 81(22).
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr.Chen did not report having any of the following types of financial relationships with industry during 2015 and/or 2016: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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