Dr. Coffey is an internationally known specialist in Tics and Tourette’s Disorder and related problems. She is Professor in the Department of Psychiatry and Chief of the Tics and Tourette’s Clinical and Research Program at the Icahn School of Medicine at Mount Sinai. She also serves as a Research Psychiatrist at the Nathan S. Kline Institute of Psychiatric Research in Orangeburg, New York. Prior to her move to the School of Medicine, Dr. Coffey was Associate Professor in the Department of Child and Adolescent Psychiatry at the NYU School of Medicine, and Director of the Tics and Tourette’s Clinical and Research Program at the NYU Child Study Center.
Am Board of Psychiatry & Neurology (Sub: Child)
Psychiatry, American Board of Psychiatry and Neurology
Dr. Coffey’s research has focused on the clinical course, comorbidity, phenomenology, and treatment of Tourette’s Disorder and related problems.
A unique focus of Dr. Coffey’s work has been comorbid anxiety and mood disorders in TD. She initially reported that separation anxiety disorder, independent of OCD, predicted greater tic severity, and that major mood disorders were a more robust predictor of functional impairment than tic severity in youth with TD. More recently, Dr. Coffey and her colleagues are investigating the neurobiology of TD with both genomics and neuroimaging techniques.
A 6-Month, Multicenter, Randomized, Safety, Tolerability, Pharmacokinetic, and Preliminary Efficacy Study of AZD5213 in Adolescents with Tourette's Disorder (TD)
The objectives of this study are to assess the safety, tolerability, pharmacokinetics, and preliminary efficacy of AZD5213 in adolescents with Tourette's Disorder (TD). Currently the only approved medications for TD are the classic neuroleptics haloperidol and pimozide. Although ...
A Pilot Study of SD-809 (deutetrabenazine) in Moderate to Severe Tourette Syndrome
This is an open label, pilot study to evaluate SD-809 for the treatment of motor and phonic tics of Tourette Syndrome (TS). The goals of the study are 1) To evaluate the safety and tolerability of treatment with SD-809 and 2) To evaluate the preliminary efficacy of SD-809 to supp...
Proof-of-Concept Safety Study of CPP-109 (Vigabatrin) for Treatment Refractory Tourette's Disorder
The purpose of this study is 1) to explore the possibility that vigabatrin will reduce tics and 2) to obtain systematic data regarding dosing, safety, and tolerability of vigabatrin in young adults with treatment refractory Tourette's Disorder (TD). Currently, the only formally a...
Guanfacine in Children with Tourette's Disorder
The purpose of this study is 1) to determine the best dose of extended release guanfacine that may be helpful in treating Tourette's Disorder (TD); 2) to better understand extended release guanfacine's adverse effects; and 3) to determine if further study of the medication is war...
Rice T, Barcak D, Garcia-Delgar B, Coffey BJ. Polycystic Ovary Syndrome and Obsessive-Compulsive Disorder: Interactions and Psychopharmacological Considerations. Journal of child and adolescent psychopharmacology 2016 Aug;.
Abdulkadir M, Tischfield JA, King RA, Fernandez TV, Brown LW, Cheon KA, Coffey BJ, de Bruijn SF, Elzerman L, Garcia-Delgar B, Gilbert DL, Grice DE, Hagstrøm J, Hedderly T, Heyman I, Hong HJ, Huyser C, Ibanez-Gomez L, Kim YK, Kim YS, Koh YJ, Kook S, Kuperman S, Lamerz A, Leventhal B, Ludolph AG, Madruga-Garrido M, Maras A, Messchendorp MD, Mir P, Morer A, Münchau A, Murphy TL, Openneer TJ, Plessen KJ, Rath JJ, Roessner V, Fründt O, Shin EY, Sival DA, Song DH, Song J, Stolte AM, Tübing J, van den Ban E, Visscher F, Wanderer S, Woods M, Zinner SH, State MW, Heiman GA, Hoekstra PJ, Dietrich A. Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder. Journal of psychiatric research 2016 Jul; 82.
Minton TB, Rosing J, Spar DS, Strawn JR, Garcia-Delgar B, Coffey BJ. Psychopharmacologic Management of Anxiety in an Adolescent with Congenital Long QT Syndrome. Journal of child and adolescent psychopharmacology 2016 Jun;.
Azova S, Rice T, Garcia-Delgar B, Coffey BJ. New-Onset Psychosis in an Adolescent with Wilson's Disease. Journal of child and adolescent psychopharmacology 2016 Apr; 26(3).
Kolli V, Mary H, Garcia-Delgar B, Coffey BJ. Quetiapine Addiction in an Adolescent. Journal of child and adolescent psychopharmacology 2016 Mar; 26(2).
Cawkwell P, Lawler A, Maneta E, Coffey BJ. Staying Up at Night: Overlapping Bipolar and Obsessive-Compulsive Disorder Symptoms in an Adolescent with Autism Spectrum Disorder. Journal of child and adolescent psychopharmacology 2016 Feb; 26(1).
Phan TD, Kostek NT, Coffey BJ. The Impact of Psychosocial Stressors on Treatment of a Teenage Girl with Obsessive Compulsive Disorder, Trichotillomania, and Anxiety. Journal of child and adolescent psychopharmacology 2015 Nov; 25(9).
Rice T, Azova S, Coffey BJ. Negative Symptoms in a Depressed Teen? Primary Hyperparathyroidism and its Psychiatric Manifestations. Journal of child and adolescent psychopharmacology 2015 Oct; 25(8).
Salau M, Adam B, Coffey BJ. Metformin in an Adolescent with Significant Weight Gain. Journal of child and adolescent psychopharmacology 2015 Sep; 25(7).
Del Pilar Trelles Thorne M, Khinda N, Coffey BJ. Posttraumatic Stress Disorder in a Child with Autism Spectrum Disorder: Challenges in Management. Journal of child and adolescent psychopharmacology 2015 Aug; 25(6).
Rice T, Coffey BJ. Pharmacotherapeutic Considerations in the Treatment of an Adolescent with Anorexia Nervosa and Obsessive Compulsive Disorder. Journal of child and adolescent psychopharmacology 2015 Jun; 25(5).
Berg A, Byrne R, Coffey BJ. Neuroleptic Malignant Syndrome in a Boy with NMDA Receptor Encephalitis. Journal of child and adolescent psychopharmacology 2015 May; 25(4).
Shah LD, Coffey BJ. Callous-unemotional traits in a child with attention-deficit/hyperactivity disorder and oppositional defiant disorder: managing medication and expectations. Journal of child and adolescent psychopharmacology 2015 Apr; 25(3).
Shaw ZA, Coffey BJ. Tics and Tourette syndrome. The Psychiatric clinics of North America 2014 Sep; 37(3).
Goodman WK, Grice DE, Lapidus KA, Coffey BJ. Obsessive-compulsive disorder. The Psychiatric clinics of North America 2014 Sep; 37(3).
Lebowitz ER, Motlagh MG, Katsovich L, King RA, Lombroso PJ, Grantz H, Lin H, Bentley MJ, Gilbert DL, Singer HS, Coffey BJ, Kurlan RM, Leckman JF. Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder. European child & adolescent psychiatry 2012 Aug; 21(8).
Gabbay V, Babb JS, Klein RG, Panzer AM, Katz Y, Alonso CM, Petkova E, Wang J, Coffey BJ. A double-blind, placebo-controlled trial of ω-3 fatty acids in Tourette's disorder. Pediatrics 2012 Jun; 129(6).
Kurlan R, Crespi G, Coffey B, Mueller-Vahl K, Koval S, Wunderlich G. A multicenter randomized placebo-controlled clinical trial of pramipexole for Tourette's syndrome. Movement disorders : official journal of the Movement Disorder Society 2012 May; 27(6).
Coffey B, Rapoport J. Guest Editors, Special issue: Tourette’s disorder and obsessive compulsive disorder. Journal of Child and Adolescent Psychopharmacology 2010; 20(4): 235-236.
Lyon GJ, Samar SM, Conelea C, Trujillo MR, Lipinski CM, Bauer CC, Brandt BC, Kemp JJ, Lawrence ZE, Howard J, Castellanos FX, Woods D, Coffey BJ. Testing tic suppression: comparing the effects of dexmethylphenidate to no medication in children and adolescents with attention-deficit/hyperactivity disorder and Tourette's disorder. Journal of child and adolescent psychopharmacology 2010 Aug; 20(4).
Lyon GJ, Samar S, Jummani R, Hirsch S, Spirgel A, Goldman R, Coffey BJ. Aripiprazole in children and adolescents with Tourette's disorder: an open-label safety and tolerability study. Journal of child and adolescent psychopharmacology 2009 Dec; 19(6).
Gabbay V, Coffey BJ, Guttman LE, Gottlieb L, Katz Y, Babb JS, Hamamoto MM, Gonzalez CJ. A cytokine study in children and adolescents with Tourette's disorder. Progress in neuro-psychopharmacology & biological psychiatry 2009 Aug; 33(6).
Budman C, Coffey BJ, Shechter R, Schrock M, Wieland N, Spirgel A, Simon E. Aripiprazole in children and adolescents with Tourette disorder with and without explosive outbursts. Journal of child and adolescent psychopharmacology 2008 Oct; 18(5).
Gabbay V, Coffey BJ, Babb JS, Meyer L, Wachtel C, Anam S, Rabinovitz B. Pediatric autoimmune neuropsychiatric disorders associated with streptococcus: comparison of diagnosis and treatment in the community and at a specialty clinic. Pediatrics 2008 Aug; 122(2).
Kurlan R, Johnson D, Kaplan EL. Streptococcal infection and exacerbations of childhood tics and obsessive-compulsive symptoms: a prospective blinded cohort study. Pediatrics 2008 Jun; 121(6).
Coffey BJ, Biederman J, Geller D, Frazier J, Spencer T, Doyle R, Gianini L, Small A, Frisone DF, Magovcevic M, Stein N, Faraone SV. Reexamining Tic persistence and Tic-associated impairment in Tourette's Disorder: findings from a naturalistic follow-up study. The Journal of nervous and mental disease 2004 Nov; 192(11).
Wilhelm S, Deckersbach T, Coffey BJ, Bohne A, Peterson AL, Baer L. Habit reversal versus supportive psychotherapy for Tourette's disorder: a randomized controlled trial. The American journal of psychiatry 2003 Jun; 160(6).
Treatment of ADHD in children with tics: a randomized controlled trial. Neurology 2002 Feb; 58(4).
Spencer TJ, Biederman J, Faraone S, Mick E, Coffey B, Geller D, Kagan J, Bearman SK, Wilens T. Impact of tic disorders on ADHD outcome across the life cycle: findings from a large group of adults with and without ADHD. The American journal of psychiatry 2001 Apr; 158(4).
Coffey BJ, Biederman J, Geller DA, Spencer TJ, Kim GS, Bellordre CA, Frazier JA, Cradock K, Magovcevic M. Distinguishing illness severity from tic severity in children and adolescents with Tourette's disorder. Journal of the American Academy of Child and Adolescent Psychiatry 2000 May; 39(5).
Coffey BJ, Biederman J, Spencer T, Geller DA, Faraone SV, Bellordre CA. Informativeness of structured diagnostic interviews in the identification of Tourette's disorder in referred youth. The Journal of nervous and mental disease 2000 Sep; 188(9).
Coffey BJ, Biederman J, Smoller JW, Geller DA, Sarin P, Schwartz S, Kim GS. Anxiety disorders and tic severity in juveniles with Tourette's disorder. Journal of the American Academy of Child and Adolescent Psychiatry 2000 May; 39(5).
Coffey BJ, Miguel EC, Biederman J, Baer L, Rauch SL, O'Sullivan RL, Savage CR, Phillips K, Borgman A, Green-Leibovitz MI, Moore E, Park KS, Jenike MA. Tourette's disorder with and without obsessive-compulsive disorder in adults: are they different?. The Journal of nervous and mental disease 1998 Apr; 186(4).
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