Click here for more information on Dr. Schaefer's 2012 Director’s New Innovator Award from the National Institutes of Health (NIH).
Dr. Schaefer is an Assistant Professor of Neuroscience and Psychiatry and a Seaver Fellow at the Friedman Brain Institute at Mount Sinai School of Medicine. She did her graduate studies at the Johannes Gutenberg University Mainz, the Charité University Berlin and The Rockefeller University in New York. In the fall of 2004 she joined Dr. Paul Greengard's Laboratory at The Rockefeller University where she completed her postdoctoral studies and was promoted to Research Associate in 2007 and Senior Research Associate in 2009. She joined the Friedman Brain Institute at Mount Sinai School of Medicine to start her own laboratory in 2011. Her research is focused on understanding how epigenetic mechanisms contribute to maintenance of specialized neuronal functions and their alteration during psychiatric and neurodegenerative diseases.
Anne Schaefer has been named a 2014 Kavli Frontiers of Science Fellow by the National Academy of Sciences (NAS). The Kavli program honors young scientists who are considered leaders in their fields and have made significant contributions to science. Jointly sponsored by the US National Academy of Sciences and The Kavli Foundation, the Kavli Frontiers of Science bring together some of the very best young scientists (under age 45) to discuss exciting advances and opportunities in their fields in a format that encourages informal collective, as well as one-on-one discussions among participants. Dr. Schaefer was invited to the Japanese-American Frontiers of Science ( JAFoS) Symposium that took place in Tokio in December 2014.
Visit Anne Schaefer's Laboratory of Brain Epigenetics for more information.
MD, Johannes Gutenberg University
MD, PhD, Charité University
Postdoc, The Rockefeller University
Comentor [COM], Neuroscience [NEU]
Technology Development Fund Award
Mount Sinai Innovation
Cure Challenge Award
Kavli Frontiers in Science Fellow
The National Academy of Science
NIH Director’s New Innovator Award
Chrissy Rossi Investigator
Seaver Autism Center
NARSAD Young Investigator Award
German Research Foundation DFG
Hans-Hench Award 2005
German Society for Immunology, Germany
Summa cum lauden
Charité University Berlin
Keystone Scholar Travel Award
USA Research Scholarship
The German National Academic Foundation
German National Merit Foundation
Gao Z, Lee P, Stafford JM, von Schimmelmann M, Schaefer A, Reinberg D. An AUTS2-Polycomb complex activates gene expression in the CNS. Nature 2014 Dec; 516(7531).
Lyons DB, Magklara A, Goh T, Sampath SC, Schaefer A, Schotta G, Lomvardas S. Heterochromatin-mediated gene silencing facilitates the diversification of olfactory neurons. Cell reports 2014 Nov; 9(3).
Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Sillivan SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, Schaefer A, Nestler EJ. G9a influences neuronal subtype specification in striatum. Nature neuroscience 2014 Apr; 17(4).
Tan CL, Plotkin JL, Venø MT, von Schimmelmann M, Feinberg P, Mann S, Handler A, Kjems J, Surmeier DJ, O'Carroll D, Greengard P, Schaefer A. MicroRNA-128 governs neuronal excitability and motor behavior in mice. Science (New York, N.Y.) 2013 Dec; 342(6163).
O'Carroll D, Schaefer A. General Principals of miRNA Biogenesis and Regulation in the Brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012 Jun;.
Schaefer A, Tarakhovsky A, Greengard P. Epigenetic mechanisms of mental retardation. Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 2011; 67.
Schaefer A, Im HI, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny PJ, O'Carroll D, Greengard P. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. The Journal of Experimental Medicine 2010 Aug; 207(9): Cover page.
Maze I, Covington HE, Dietz DM, LaPlant Q, Renthal W, Russo SJ, Mechanic M, Mouzon E, Neve RL, Haggarty SJ, Ren Y, Sampath SC, Hurd YL, Greengard P, Tarakhovsky A, Schaefer A, Nestler EJ. Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science 2010 Jan; 327(5962).
Schaefer A, Sampath SC, Intrator A, Min A, Gertler TS, Surmeier DJ, Tarakhovsky A, Greengard P. Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron 2009 Dec; 64(5).
Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, Surmeier DJ, Greengard P, Heintz N. A translational profiling approach for the molecular characterization of CNS cell types. Cell 2008 Nov; 135(4): Cover page.
Schaefer A, O'Carroll D, Tan CL, Hillman D, Sugimori M, Llinas R, Greengard P. Cerebellar neurodegeneration in the absence of microRNAs. The Journal of Experimental Medicine 2007 Jul; 204(7): Cover page .
Meffre E, Schaefer A, Wardemann H, Wilson P, Davis E, Nussenzweig MC. Surrogate light chain expressing human peripheral B cells produce self-reactive antibodies. The Journal of Experimental Medicine 2004 Jan; 199(1).
Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. Predominant autoantibody production by early human B cell precursors. Science 2003 Sep; 301(5638).
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Dr.Schaefer did not report having any of the following types of financial relationships with industry during 2015 and/or 2016: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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