- ASSISTANT PROFESSOR | Environmental Medicine & Public Health
Allan Just, PhD is an environmental epidemiologist and serves as an Assistant Professor in the Department of Environmental Medicine and Public Health. His research interests are in children’s environmental health, computational methods for epigenomics, environmental epigenomics, endocrine disrupting compounds, and air pollution modeling using satellite data. He uses large datasets, computational tools, and the methods of molecular epidemiology to investigate links between environmental exposures and children's health.
Dr. Just's R00 grant is based in the Mexico City cohort of the Programming Research in Obesity, Growth, Environment, and Social Stressors (PROGRESS) study as well as the Programming of Intergenerational Stress Mechanisms (PRISM) study. He is collaborating with the National Institute of Public Health, Mexico on a grant from the Mexican National Council of Science and Technology (CONACyT) that addresses air pollution and health using the Mexican National Health and Nutrition Examination Survey (ENSANUT). He is also in the coordinating groups for several epigenomic meta-analyses as part of the Prenatal and Childhood Epigenetics (PACE) consortium and the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
Dr. Just received his PhD in Environmental Health Sciences from Columbia University in 2012. Since 2012 he completed a postdoctoral fellowship in Environmental Epigenetics at the Harvard T.H. Chan School of Public Health, before joining the Icahn School of Medicine at Mount Sinai in September of 2015. Dr Just is a past recipient of an EPA STAR graduate fellowship for his dissertation work on phthalate mixtures and children’s respiratory health and was awarded a K99/R00 grant from the National Institute of Environmental Health Sciences entitled “Prenatal Exposure to Endocrine Disrupters, DNA Methylation, and Childhood Obesity” (R00ES023450).
Epigenetics, Molecular Epidemiology
Prenatal Exposure to Endocrine Disrupters, DNA Methylation, and Childhood Obesity NIEHS
Knight AK, Craig JM, Theda C, Bækvad-Hansen M, Bybjerg-Grauholm J, Hansen CS, Hollegaard MV, Hougaard DM, Mortensen PB, Weinsheimer SM, Werge TM, Brennan PA, Cubells JF, Newport DJ, Stowe ZN, Cheong JL, Dalach P, Doyle LW, Loke YJ, Baccarelli AA, Just AC, Wright RO, Téllez-Rojo MM, Svensson K, Trevisi L, Kennedy EM, Binder EB, Iurato S, Czamara D, Räikkönen K, Lahti JM, Pesonen AK, Kajantie E, Villa PM, Laivuori H, Hämäläinen E, Park HJ, Bailey LB, Parets SE, Kilaru V, Menon R, Horvath S, Bush NR, LeWinn KZ, Tylavsky FA, Conneely KN, Smith AK. An epigenetic clock for gestational age at birth based on blood methylation data. Genome biology 2016 Oct; 17(1).
Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, Moreno-Macias H, Smith JA, Brody JA, Dhingra R, Yousefi P, Pankow JS, Kunze S, Shah S, McRae AF, Lohman K, Sha J, Absher DM, Ferrucci L, Zhao W, Demerath EW, Bressler J, Grove ML, Huan T, Liu C, Mendelson MM, Yao C, Kiel DP, Peters A, Wang-Sattler R, Visscher PM, Wray NR, Starr JM, Ding J, Rodriguez CJ, Wareham NJ, Irvin MR, Zhi D, Barrdahl M, Vineis P, Ambatipudi S, Uitterlinden AG, Hofman A, Schwartz J, Colicino E, Hou L, Vokonas PS, Hernandez DG, Singleton AB, Bandinelli S, Turner ST, Ware EB, Smith AK, Klengel T, Binder EB, Psaty BM, Taylor KD, Gharib SA, Swenson BR, Liang L, DeMeo DL, O'Connor GT, Herceg Z, Ressler KJ, Conneely KN, Sotoodehnia N, Kardia SL, Melzer D, Baccarelli AA, van Meurs JB, Romieu I, Arnett DK, Ong KK, Liu Y, Waldenberger M, Deary IJ, Fornage M, Levy D, London SJ. Epigenetic Signatures of Cigarette Smoking. Circulation. Cardiovascular genetics 2016 Sep;.
Nwanaji-Enwerem JC, Colicino E, Trevisi L, Kloog I, Just AC, Shen J, Brennan K, Dereix A, Hou L, Vokonas P, Schwartz J, Baccarelli AA. Long-term ambient particle exposures and blood DNA methylation age: findings from the VA normative aging study. Environmental epigenetics 2016 Jun; 2(2).
Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, Salas LA, Baïz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor JA, Duijts L, Sharp GC, Jankipersadsing SA, Nilsen RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Bustamante M, Saurel-Coubizolles MJ, Quraishi BM, Ren J, Tost J, Gonzalez JR, Peters MJ, Håberg SE, Xu Z, van Meurs JB, Gaunt TR, Kerkhof M, Corpeleijn E, Feinberg AP, Eng C, Baccarelli AA, Benjamin Neelon SE, Bradman A, Merid SK, Bergström A, Herceg Z, Hernandez-Vargas H, Brunekreef B, Pinart M, Heude B, Ewart S, Yao J, Lemonnier N, Franco OH, Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles MA, Holloway J, Auffray C, Tiemeier HW, Smith GD, Postma D, Hivert MF, Eskenazi B, Vrijheid M, Arshad H, Antó JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy SK, DeMeo DL, Burchard EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VW, Wilcox A, Melén E, London SJ. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. American journal of human genetics 2016 Apr; 98(4).
Sorek-Hamer M, Just AC, Kloog I. Satellite remote sensing in epidemiological studies. Current opinion in pediatrics 2016 Feb;.
Rosa MJ, Just AC, Tamayo Y Ortiz M, Schnaas L, Svensson K, Wright RO, Téllez Rojo MM, Wright RJ. Prenatal and postnatal stress and wheeze in Mexican children: Sex-specific differences. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2016 Jan;.
Panni T, Mehta AJ, Schwartz JD, Baccarelli AA, Just AC, Wolf K, Wahl S, Cyrys J, Kunze S, Strauch K, Waldenberger M, Peters A. A Genome-Wide Analysis of DNA Methylation and Fine Particulate Matter Air Pollution in Three Study Populations: KORA F3, KORA F4, and the Normative Aging Study. Environmental health perspectives 2016 Jan;.
Just AC, Miller RL, Perzanowski MS, Rundle AG, Chen Q, Jung KH, Hoepner L, Camann DE, Calafat AM, Perera FP, Whyatt RM. Vinyl flooring in the home is associated with children's airborne butylbenzyl phthalate and urinary metabolite concentrations. Journal of exposure science & environmental epidemiology 2015 Nov; 25(6).
Burris HH, Baccarelli AA, Byun HM, Cantoral A, Just AC, Pantic I, Solano-Gonzalez M, Svensson K, Tamayo Y Ortiz M, Zhao Y, Wright RO, Téllez-Rojo MM. Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight. Epigenetics 2015 Oct; 10(10).
Chen J, Just AC, Schwartz J, Hou L, Jafari N, Sun Z, Kocher JA, Baccarelli A, Lin X. CpGFilter: model-based CpG probe filtering with replicates for epigenome-wide association studies. Bioinformatics (Oxford, England) 2015 Oct;.
Sanders AP, Burris HH, Just AC, Motta V, Amarasiriwardena C, Svensson K, Oken E, Solano-Gonzalez M, Mercado-Garcia A, Pantic I, Schwartz J, Tellez-Rojo MM, Baccarelli AA, Wright RO. Altered miRNA expression in the cervix during pregnancy associated with lead and mercury exposure. Epigenomics 2015 Sep;.
Just AC, Wright RO, Schwartz J, Coull BA, Baccarelli AA, Tellez-Rojo MM, Moody E, Wang Y, Lyapustin A, Kloog I. Using High-Resolution Satellite Aerosol Optical Depth To Estimate Daily PM2.5 Geographical Distribution in Mexico City. Environmental science & technology 2015 Jul; 49(14).
Raz R, Roberts AL, Lyall K, Hart JE, Just AC, Laden F, Weisskopf MG. Autism spectrum disorder and particulate matter air pollution before, during, and after pregnancy: a nested case-control analysis within the Nurses' Health Study II Cohort. Environmental health perspectives 2015 Mar; 123(3).
Lakshmanan A, Chiu YH, Coull BA, Just AC, Maxwell SL, Schwartz J, Gryparis A, Kloog I, Wright RJ, Wright RO. Associations between prenatal traffic-related air pollution exposure and birth weight: Modification by sex and maternal pre-pregnancy body mass index. Environmental research 2015 Feb; 137.
Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin MD, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ. DNA methylation age of blood predicts all-cause mortality in later life. Genome biology 2015 Jan; 16.
Sanders AP, Burris HH, Just AC, Motta V, Svensson K, Mercado-Garcia A, Pantic I, Schwartz J, Tellez-Rojo MM, Wright RO, Baccarelli AA. microRNA expression in the cervix during pregnancy is associated with length of gestation. Epigenetics 2015; 10(3).
Whyatt RM, Rundle AG, Perzanowski MS, Just AC, Donohue KM, Calafat AM, Hoepner L, Perera FP, Miller RL. Prenatal phthalate and early childhood bisphenol A exposures increase asthma risk in inner-city children. The Journal of allergy and clinical immunology 2014 Nov; 134(5).
Whyatt RM, Perzanowski MS, Just AC, Rundle AG, Donohue KM, Calafat AM, Hoepner LA, Perera FP, Miller RL. Asthma in inner-city children at 5-11 years of age and prenatal exposure to phthalates: the Columbia Center for Children's Environmental Health Cohort. Environmental health perspectives 2014 Oct; 122(10).
Karwowski MP, Just AC, Bellinger DC, Jim R, Hatley EL, Ettinger AS, Hu H, Wright RO. Maternal iron metabolism gene variants modify umbilical cord blood lead levels by gene-environment interaction: a birth cohort study. Environmental health : a global access science source 2014 Oct; 13.
Braun JM, Just AC, Williams PL, Smith KW, Calafat AM, Hauser R. Personal care product use and urinary phthalate metabolite and paraben concentrations during pregnancy among women from a fertility clinic. Journal of exposure science & environmental epidemiology 2014 Sep-Oct; 24(5).
Burris HH, Baccarelli AA, Motta V, Byun HM, Just AC, Mercado-Garcia A, Schwartz J, Svensson K, Téllez-Rojo MM, Wright RO. Association between length of gestation and cervical DNA methylation of PTGER2 and LINE 1-HS. Epigenetics 2014 Aug; 9(8).
Braun JM, Kalkbrenner AE, Just AC, Yolton K, Calafat AM, Sjödin A, Hauser R, Webster GM, Chen A, Lanphear BP. Gestational exposure to endocrine-disrupting chemicals and reciprocal social, repetitive, and stereotypic behaviors in 4- and 5-year-old children: the HOME study. Environmental health perspectives 2014 May; 122(5).
Roberts AL, Lyall K, Hart JE, Laden F, Just AC, Bobb JF, Koenen KC, Ascherio A, Weisskopf MG. Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses' Health Study II participants. Environmental health perspectives 2013 Aug; 121(8).
Hoepner LA, Whyatt RM, Just AC, Calafat AM, Perera FP, Rundle AG. Urinary concentrations of bisphenol A in an urban minority birth cohort in New York City, prenatal through age 7 years. Environmental research 2013 Apr; 122.
Donohue KM, Miller RL, Perzanowski MS, Just AC, Hoepner LA, Arunajadai S, Canfield S, Resnick D, Calafat AM, Perera FP, Whyatt RM. Prenatal and postnatal bisphenol A exposure and asthma development among inner-city children. The Journal of allergy and clinical immunology 2013 Mar; 131(3).
Just AC, Whyatt RM, Miller RL, Rundle AG, Chen Q, Calafat AM, Divjan A, Rosa MJ, Zhang H, Perera FP, Goldstein IF, Perzanowski MS. Children's urinary phthalate metabolites and fractional exhaled nitric oxide in an urban cohort. American journal of respiratory and critical care medicine 2012 Nov; 186(9).
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Dr.Just did not report having any of the following types of financial relationships with industry during 2016 and/or 2017: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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