Uterine Cancer Treatment

Most patients have surgery to remove as much of the uterine tumor as possible.

The different types of surgery may include:

  • Hysterectomy: A surgical procedure to remove the uterus, including the cervix. If the uterus and cervix are taken out through the vagina, the operation is called a vaginal hysterectomy. If the uterus and cervix are taken out through a large incision in the abdomen, the operation is called a total abdominal hysterectomy. If the uterus and cervix are taken out through a small incision in the abdomen using a laparoscope, the operation is called a total laparoscopic hysterectomy.

  • Unilateral salpingo-oophorectomy: A surgical procedure to remove one ovary and one fallopian tube.

  • Bilateral salpingo-oophorectomy: A surgical procedure to remove both ovaries and both fallopian tubes. Different types of treatment are available for patients with endometrial cancer including surgery to remove as much of the tumor as possible.

Even if the doctor removes all the cancer that can be seen at the time of the surgery, some patients may be given radiation therapy or hormone treatment after surgery to kill any cancer cells that are left. Treatment given after the surgery to lower the risk of cancer reoccurrence is called 'adjuvant therapy.'


Radiation therapy refers to the use of high-energy X-rays or other types of radiation to kill cancer cells or keep them from growing. With external radiation therapy, a machine outside your body directs radiation at your cancer. With internal radiation therapy, a radioactive substance sealed in needles, seeds, wires, or catheters is placed inside your body in or near your cancer. Whether you receive internal or external radiation depends on the type and stage of your cancer. Some women instead undergo intraperitoneal radiation therapy, in which radioactive liquid is injected directly in their abdomen through a catheter to kill the cancer or keep it from spreading.

The type of radiation therapy you receive depends on the stage of your cancer.

Chemotherapy uses drugs to stop the growth of cancer cells, either by killing the cells or by keeping them from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the spinal column, an organ, or a body cavity, such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). Delivering anticancer drugs directly into the peritoneal cavity (the space that contains the abdominal organs) through a thin tube is called intraperitoneal chemotherapy. Whether you receive regional, systemic, or intraperitoneal chemotherapy depends on the type and stage of your cancer.

Hormone therapy is a cancer treatment that removes hormones (substances made by glads in your body and circulated into the bloodstream) and stops cancer cells from growing. Some hormones can cause certain cancers to grow.

Treatments in Development

New cancer treatments in development include:

  • Biologic therapy: This treatment uses your immune system to fight cancer. The idea is to use substances made by your bodyor replicated in a lab to boost, direct, or restore your body's natural defenses against cancer. This type of cancer treatment is also called biotherapy or immunotherapy.

  • Targeted therapy: This treatment uses drugs or other substances to identify and attack specific cancer cells without harming normal cells.

Clinical Trials

For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are conducted to find out if new cancer treatments are safe and effective or better than the standard treatment.

Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment. Your participation may help improve the way cancer is treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.

Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or that reduce the side effects of cancer treatment.

Clinical trials are taking place in many parts of the country. To learn more about the clinical trials that Mount Sinai is participating in, visit our clinical trials page. Type in "ovarian cancer" and hit "Search Clinical Trials."


Some of the tests you underwent to diagnose your condition or to determine the stage of your cancer may have to be repeated. Other tests will be repeated to see how well your treatment is working. Decisions about whether to continue, change, or stop treatment may be based on the results of these tests. This is sometimes called re-staging.

Even after you have completed treatment, your doctor may order tests from time to time to see if your condition has changed or if your cancer has come back. These tests are sometimes called follow-up tests or check-ups.

To make an appointment with a Mount Sinai gynecologic oncologist, please call us at 212-427-9898 or 212-241-1111.

Contact Us

To make an appointment with a Mount Sinai gynecologic oncologist, please contact us at 212-427-9898 or 212-241-1111.

Ruttenberg Treatment Center
1470 Madison Avenue, 3rd Floor
New York, NY 10029