(HCV; Hep C)
Hepatitis C is an infection of the liver.
Hepatitis C is caused by the hepatitis C virus (HCV). The hepatitis C virus is spread through contact with the blood of an infected person.
A woman with hepatitis can pass the virus on to her baby during birth. The hepatitis C virus is not spread through food or water.
Factors that may increase your chance of hepatitis C include:
- Injecting illicit drugs, especially with shared needles
- Receiving a blood transfusion before 1992—this risk is low in the United States
- Receiving blood clotting products before 1987
- Receiving an HCV-infected organ transplant
- Long-term kidney dialysis treatment
- Sharing toothbrushes, razors, nail clippers, or other personal hygiene items that have HCV-infected blood on them
- Being accidentally stuck by an HCV-infected needle—a concern for healthcare workers
- Frequent contact with HCV-infected people—a concern for healthcare workers
- Body piercing
- Having sex with partners who have hepatitis C or other sexually transmitted diseases
Most people with hepatitis C do not have symptoms. Over time, the disease can cause serious liver damage.
Symptoms may include:
- Loss of appetite
- Yellowing of the eyes and skin
- Darker colored urine
- Loose, light, or chalky colored stools
- Abdominal pain
- Aches and pains
- Joint pain
- Cigarette smokers may suddenly dislike the taste of cigarettes
Chronic hepatitis C may cause some of the above symptoms, as well as:
- Severe fatigue
- Loss of appetite
Serious complications of hepatitis C include:
You will be asked about your symptoms and medical history. A physical exam will be done. You will also discuss your risk factors.
Your bodily fluids and tissues may be tested. This can be done with:
- Blood tests
- Liver biopsy—tissue is examined under a microscope
Your liver function may be evaluated. This can be done with liver function studies.
Images may be needed of your liver. This can be done with an ultrasound.
Hepatitis C is usually treated with combined therapy, consisting of:
- Medication to boost the immune system
- Antiviral medications
You will be advised to stop drinking alcohol and smoking, which can further damage your liver, especially when undergoing treatment. If you have problems stopping alcohol, your doctor can refer you to counseling or a treatment program. There are several ways to successfully quit smoking .
In unsuccessful cases, chronic hepatitis C can cause cirrhosis and serious liver damage. A liver transplant may be needed, although it does not typically cure hepatitis C.
To prevent becoming infected with hepatitis C:
- Do not inject illegal drugs. Shared needles have the highest risk. Seek help to stop using drugs.
- Do not have sex with partners who have sexually transmitted diseases (STDs).
- Practice safe sex (using latex condoms) or abstain from sex.
- Limit your number of sexual partners.
Do not share personal items that might have blood on them, such as:
- Manicuring tools
- Pierced earrings
- Avoid handling items that may be contaminated by HCV-infected blood.
- Donate your own blood before elective surgery to be used if you need a blood transfusion.
- Go to regular check ups and get tested for hepatitis C and other STDs as advised.
To prevent spreading hepatitis C to others if you are infected:
American Liver Foundation
Hepatitis Foundation International
Canadian Liver Foundation
2015 Sexually transmitted diseases treatment guidelines. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/std/tg2015/default.htm. Updated October 6, 2015. Accessed October 8, 2015.
Centers for Disease Control and Prevention (CDC). Sexual transmission of hepatitis C virus among HIV-infected men who have sex with men—New York City, 2005-2010. MMWR Morb Mortal Wkly Rep. 2011;60(28):945-950.
Chang MH, Gordon LA, Fung HB. Boceprevir: A protease inhibitor for the treatment of hepatitis C. Clin Ther. 2012;34(10):2021-2138.
Explore blood transfusion? National Heart Lung and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/bt. Updated January 30, 2012. Accessed October 8, 2015.
Hepatitis C. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated July 6, 2015. Accessed October 8, 2015.
Viral hepatitis—hepatitis C information. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/hepatitis/hcv/index.htm. Updated May 31, 2015. Accessed October 8, 2015.
What I need to know about hepatitis C. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.niddk.nih.gov/health-information/health-topics/liver-disease/hepatitis-c/Pages/ez.aspx. Updated December 19, 2012. Accessed October 8, 2014.
12/9/2013 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: US Food & Drug Administration. FDA news release: FDA approves new treatment for hepatitis C virus. Food & Drug Administration website. Accessed October 8, 2015.
4/29/2014 12/9/2013 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: American Association for the Study of Liver Diseases/Infectious Diseases Society of America (AASLD/IDSA) recommendations on testing, managing, and treating hepatitis C. Available at: http://www.hcvguidelines.org/fullreport. Accessed October 8, 2015.
10/8/2014 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: British Association of Sexual Health and HIV (BASHH) recommendations on testing for sexually transmitted infections in men who have sex with men. Available at: http://www.bashh.org/documents/BASHH%20Recommendations%20for%20testing%20for%20STIs%20in%20MSM%20-%20FINAL.pdf. Accessed October 8, 2015.
Last reviewed August 2015 by Daus Mahnke, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.