Icahn School of Medicine at Mount Sinai Joins Autism BrainNet Tissue Bank
Consortium of premiere research institutions will provide critically needed brain tissue for autism research
The Icahn School of Medicine at Mount Sinai has joined Autism BrainNet, a new network of research institutions created to collect, store and distribute postmortem brain tissue resources that will help scientists gain a deeper understanding of the causes, treatment and cure of autism spectrum disorder, which now affects an estimated one in 68 children. Launched by the Simons Foundation and Autism Speaks, Autism BrainNet recently joined with the Autism Science Foundation to unveil the Autism BrainNet registration site, It Takes Brains.
“In order for researchers to understand the fundamental genetic and neuropathological aspects of autism spectrum disorder, the study of brain tissue from individuals with autism spectrum disorder is essential, but there is a shortage of donated tissue,” says Patrick R. Hof, MD, Vice-Chair for the Department of Neuroscience at the Icahn School of Medicine at Mount Sinai and New York Node Director for Autism BrainNet. “While we know autism is a neurological disorder, the alterations in brain structure and function that account for this widespread and lifelong behavioral disorder remain unknown. Gaining this understanding will influence how we develop strategies for prevention and effective treatment.”
Previous research on brain tissue has shown that autistic brains are structurally different in the number and size of neurons. There are also mutations in several genes related to synapse function. Autistic brains may have higher levels of inflammation compared to the brains of those who do not suffer from the disorder. However, more widespread data and study has been stymied by the shortage of brain tissue samples.
The Seaver Autism Center at the Icahn School of Medicine at Mount Sinai will serve as a collection and storage site for brain tissue samples, receiving samples from the metropolitan New York area and beyond. Other inaugural members of the Autism BrainNet include the University of California MIND Institute in Sacramento, the Harvard University/Beth Israel Deaconess Medical Center in Boston, and the University of Texas at Southwestern Medical School in Dallas. Additional sites, including international nodes, are expected to join in the future.
The term “autism” describes a set of brain disorders caused by either genetic, environmental or the combined effects of both. The disorders are characterized by communicational, social and behavioral difficulties as well as repetitive behaviors.
Autism BrainNet is expected to enable researchers to gain new insights into the disorder, which will aid future research and possible treatment. The focus of the newly launched “It Takes Brains” registration site is to educate families affected by autism so they may better understand the need for brain tissue donation and to encourage their registration with Autism BrainNet to increase potential donations.
To learn more, please call: 1-877-333-0990 or visit www.autismbrainnet.org and www.takesbrains.org
About the Mount Sinai Health System
Mount Sinai Health System is one of the nation’s leading integrated academic health systems and one of the largest in the New York metropolitan area. The Health System includes approximately 48,000 employees, more than 9,000 physicians, and 8,600 nurses across seven hospitals, more than 400 outpatient practices, over 600 research and clinical laboratories, a school of nursing, and schools of medicine and graduate school of biomedical sciences.
As a leading learning health system, Mount Sinai combines clinical expertise with scientific discovery to improve patient care while training the next generation of health care and biomedical leaders. The Health System provides care across every stage of life, from prenatal care through geriatrics, while advancing personalized medicine through artificial intelligence, data science, and biomedical research.
Mount Sinai is consistently recognized among the nation’s leading academic health systems for patient care, research, and education. The Mount Sinai Hospital is ranked No. 1 in New York and recognized as one of the world’s top Smart Hospital by Newsweek. The Icahn School of Medicine at Mount Sinai ranks No. 11 among U.S. medical schools for National Institutes of Health (NIH) funding and No. 1 among freestanding medical schools, reflecting the strength of its scientific enterprise and leadership in biomedical research.
For more information, visit https://www.mountsinai.org or find Mount Sinai on Facebook, Instagram, LinkedIn, X, and YouTube. To listen to news and stories from Mount Sinai, visit the Mount Sinai Podcast Network.