Next Avenue – "Should You Request the Genetic Test That Angelina Jolie Opted For?"
Angelina Jolie's decision highlights the importance of knowing your family medical history.
Angelina Jolie was found to have a mutation in the gene known as BRCA1. Mutations in that gene, and another known as BRCA2, are estimated to be the cause of 5 to 10 percent of breast cancers and 10 to 15 percent of ovarian cancers among white women in the United States. "These are genes that every human being has, but not everyone has mutations in them," says Dr. David Fishman, a professor in the division of gynecologic oncology at The Mount Sinai Medical Center. About 1 in 1,000 women carry a BRCA mutation.
- Dr. David Fishman, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai