Pituitary Treatments and Surgery
The Pituitary Care and Research Center at Mount Sinai is the premier destination for the management and treatment of various pituitary tumors and disorders, offering advanced innovative neurosurgical techniques in treating the most complex of cases. Our specialists focus on multimodal approaches to treat the full spectrum of these diseases.
Medical therapy may be one course of action to treat the symptoms associated with pituitary tumors, or it may be used in conjunction with other therapies.
Medications, such as dopamine agonists, can stop tumors such as prolactinomas, growth hormone tumors, ACTH-secreting tumors, and thyrotropin (TSH)-secreting tumors from overproducing hormones. Dopamine agonist medications work especially well for prolactinomas, usually shrinking most of these tumors. Other medical therapies can include somatostatin analogues, growth hormone receptor antagonists, glucocorticoid receptor antagonists, cortisol biosynthesis inhibitors, and more.
Additional medication may be prescribed, depending on the symptoms associated with the pituitary tumor.
For large tumors or tumors that fail to respond to medical therapy, pituitary surgery may be recommended. Surgery may also be used in conjunction with medication therapy.
In collaboration with our neuroendocrinologists, our expert neurosurgeons determine the best trajectory for surgery in removing the tumor. This may include a minimally invasive procedure called transsphenoidal surgery, using a tiny endoscope and surgical instruments to remove the tumor through the nose and the sphenoid bone. This eliminates the need for large incisions and speeds up the healing process.
The Neurosurgery Department at The Mount Sinai Hospital has performed more than 3,000 of these surgeries that usually require a two-night hospital stay. Patients are seen within two weeks for follow-up.
Another option for treatment includes radiation therapy in the form of multiple doses or with one targeted session using advanced stereotactic radiosurgery technology. This therapy uses targeted beams of radiation to kill the pituitary tumor cells. It may be used along with surgical or medical therapy, depending on the treatment plan developed by the care team.