Facial Plastic and Reconstructive Surgery Research

Mount Sinai’s Division of Facial Plastic and Reconstructive Surgery has long been recognized as a pioneer in both cosmetic and reconstructive surgery of the face, head and neck. Our Facial Plastic and Reconstructive surgeons continue that tradition today with ongoing clinical trials and research aimed at building on the division’s history of clinical excellence and leadership. We are currently recruiting patients for the following two clinical trials.

Manuka Honey Dressings for Local Wound Care

Principal Investigator: Joshua D. Rosenberg, MD
Mount Sinai Institutional Review Board Identifier: IF1549844
Status: Recruiting Patients

Since antiquity, honey has been recognized for its healing properties. Literature about the use of medicinal honey for wound care dates back centuries with recent data suggesting its use in patients suffering from burns or pressure ulcers. Research has shown Manuka honey (Leptospermum scoparium) to have significant immune benefits and the ability to influence all phases of wound healing: inflammation, proliferation and remodeling. In addition, numerous clinical studies have identified positive benefits for wound healing. However, there is a lack of prospective, randomized controlled data on the use of honey as a medicinal agent in local wound care and scar healing.

In order to better understand Manuka Honey’s ability to aid in healing, we are conducting a randomized, controlled, single-blinded study of patients undergoing reconstructive surgery. This project uses split thickness skin graft and free tissue transfer donor sites as standard wound models to compare the effects of Manuka Honey versus standard wound care therapies. Through the use of standard wound model and objective measurement tools, we hope to better elucidate any benefits of this novel wound care ‘technology.’

This project is currently recruiting patients. If you would like to learn more about this study or any other of our ongoing research projects, please contact us at
212-241-9410. Additional information can also be found at ClinicalTrials.gov.

Facial Nerve Palsy/Paralysis Treatment Outcomes

Principal Investigator: Joshua D. Rosenberg, MD
Mount Sinai Institutional Review Board Identifier: IF1564716
Status: Recruiting Patients

Facial nerve paralysis represents a severe form of facial disfigurement with significant psychological, social, and functional consequences. Bells Palsy is a common cause of facial paralysis but multiple other causes exist. Patients with facial nerve paralysis experience significant psychological and social consequences. Affected patients have difficulty expressing emotions and higher rates of social isolation and depression. Along with psychological and social consequences, facial nerve paralysis can result in difficulty eye problems and blindness due to an inability to blink and problems with eating and speaking. For many patients uncomfortable and uncontrollable muscle spasms (synkinesis) may also develop overtime.

Multiple treatment options exist for patients with facial nerve paralysis, whether due to Bell’s Palsy or other causes. These options range from physical therapy to surgery depending on the degree of dysfunction. Although many types of surgeries and treatments have been described in the medical literature, we still lack a complete understanding of which treatments are best for specific patients. The purpose of this research is to assess outcomes of all patients we treat with facial nerve paralysis. Using state-of-the-art assessment tools and video/photographic analysis, we hope to better understand how to tailor facial paralysis treatment to each individual patient’s needs.

This project is currently recruiting patients. If you would like to learn more about this study or any other of our ongoing research projects, please contact us at
212-241-9410. Additional information can also be found at ClinicalTrials.gov.

Contact Us

Facial Plastic and Reconstructive Surgery
5 East 98th Street, 8th Floor
New York, NY 10029

Make an appointment:
Tel: 212-241-9410

Mount Sinai Doctors
2025 Richmond Road
Staten Island, NY 10306

Make an appointment:
Tel: 718-420-1279