Arteritis - temporal; Cranial arteritis; Giant cell arteritis
Temporal arteritis is inflammation and damage to the blood vessels that supply blood to the head, neck, upper body and arms. It is also called giant cell arteritis.
Temporal arteritis affects medium-to-large arteries. It causes inflammation, swelling, tenderness, and damage to the blood vessels that supply blood to the head, neck, upper body, and arms. It most commonly occurs in the arteries around the temples (temporal arteries). These arteries branch off from the carotid artery in the neck. In some cases, the condition can occur in medium-to-large arteries in other places in the body as well.
The cause of the condition is unknown. It is believed to be due in part to a faulty immune response. The disorder has been linked to some infections and to certain genes.
The problem may develop with or after another inflammatory disorder known as polymyalgia rheumatica. Giant cell arteritis almost always occurs in people over age 50. It is most common in people of northern European descent. The condition may run in families.
Some common symptoms of this problem are:
- Throbbing headache on one side of the head or the back of the head
- Tenderness when touching the scalp
Other symptoms may include:
- General ill feeling
- Jaw pain that occurs when chewing
- Pain in the arm after using it
- Muscle aches
- Pain and stiffness in the neck, upper arms, shoulder, and hips
- Weakness, excessive tiredness
Problems with eyesight may occur, and at times may begin suddenly. These problems include:
- Blurred vision
- Double vision
- Reduced vision (blindness in one or both eyes)
Other symptoms may occur with this disease, including:
Exams and Tests
The health care provider will examine your head.
- The scalp is often sensitive to touch.
- There may be a tender, thick artery on one side of the head, most often over one or both temples.
Blood tests may include:
Blood tests alone cannot provide a diagnosis. You will need to have a biopsy (tissue sample) from the involved artery.
You may also have other tests, including:
Getting prompt treatment can help prevent severe problems such as blindness or even stroke.
Most of the time, you will receive corticosteroids, such as prednisone, by mouth. These medicines are often started even before a biopsy is done. You may also be told to take aspirin.
Most people begin to feel better within a few days after starting treatment. However, you will need to take medicine for 1 to 2 years. The dose of corticosteroids will be cut back very slowly.
Biologic medicines may also be used. These medicines appear to reduce the amount of corticosteroids needed to control the disease.
Long-term treatment with corticosteroids can make bones thinner and increase your chance of a fracture. You will need to take the following steps to protect your bone strength.
- Avoid smoking and excess alcohol intake.
- Take extra calcium and vitamin D (based on your provider's advice).
- Start walking or other forms of weight-bearing exercises.
- Have your bones checked with a bone mineral density (BMD) test or DEXA scan.
- Take a bisphosphonate medicine, such as alendronate (Fosamax), as prescribed by your provider.
Most people make a full recovery, but treatment may be needed for 1 to 2 years or longer. The condition may return at a later date.
Damage to other blood vessels in the body, such as aneurysms (ballooning of the blood vessels), may occur. This damage can lead to a stroke in the future.
When to Contact a Medical Professional
Call your provider if you have:
- Throbbing headache that does not go away
- Loss of vision
- Other symptoms of temporal arteritis
There is no known prevention.
Hellmann DB. Giant cell arteritis, polymyalgia rheumatica, and Takayasu's arteritis. In: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley and Firestein's Textbook of Rheumatology. 10th ed. Philadelphia, PA: Elsevier; 2017:chap 88.
Ponte C, Rodrigues AF, O'Neill L, Luqmani RA. Giant cell arteritis: current treatment and management. World J Clin Cases. 2015;3(6):484-494. PMID: 26090367
Last reviewed on: 2/8/2017
Reviewed by: Gordon A. Starkebaum, MD, Professor of Medicine, Division of Rheumatology, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.