Niemann-Pick disease

NPD; Sphingomyelinase deficiency; Lipid storage disorder - Niemann-Pick disease; Lysosomal storage disease - Niemann-Pick

Niemann-Pick disease (NPD) is a group of diseases passed down through families (inherited) in which fatty substances called lipids collect in the cells of the spleen, liver, and brain.

There are 3 common forms of the disease:

  • Type A
  • Type B
  • Type C

Each type involves different organs. It may or may not involve the nervous system and breathing. Each one can cause different symptoms and may occur at different times throughout life.

Niemann-Pick foamy cells

Neimann-Pick is a disease in which excess material is stored inside cells (metabolic storage disease). These cells are referred to as "foam cells" because of their foamy or soap-suds appearance.

Causes

Symptoms

Exams and Tests

Treatment

Support Groups

Outlook (Prognosis)

When to Contact a Medical Professional

Prevention