Giardia infection
Giardia;G. duodenalis; G. intestinalis; Traveler's diarrhea - giardiasis
Giardia, or giardiasis, is a parasitic infection of the small intestine. A tiny parasite called Giardia lamblia causes it.
The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.
Giardiasis is an intestinal infection caused by a protozoan and is spread by contaminated water or contact with an infected person. People who are travelling or hiking should assume water sources are contaminated and either purify drinking water or drink bottled water. Healthcare or daycare workers should practice good hygiene when going from person to person. Unprotected anal sex can also transmit Giardiasis from an infected person to the partner.
Workers in daycare centers or institutions such as hospitals and eldercare should use good handwashing and hygienic techniques when going from child to child or patient to patient.
The digestive system organs in the abdominal cavity include the liver, gallbladder, stomach, small intestine and large intestine.
Causes
The giardia parasite lives in soil, food, and water. It may also be found on surfaces that have come into contact with animal or human waste.
You may become infected if you:
- Are exposed to a family member with giardiasis
- Drink water from lakes or streams where animals such as beavers and muskrats, or domestic animals such as sheep, have left their waste
- Eat raw or undercooked food that has been contaminated with the parasite
- Have direct person-to-person contact in daycare centers, long-term care homes, or nursing homes with people who are infected with the parasite
- Have unprotected anal sex
Travelers are at risk for giardiasis throughout the world. Campers and hikers are at risk if they drink untreated water from streams and lakes.
Symptoms
The time between becoming infected and symptoms is 7 to 14 days.
Non-bloody diarrhea is the main symptom. Other symptoms include:
- Abdominal gas or bloating
- Headache
- Loss of appetite
- Low-grade fever
- Nausea
- Weight loss and loss of body fluids
Some people who have had a giardia infection for a long time continue having symptoms, even after the infection is gone.
Exams and Tests
Tests that may be done include:
- Stool antigen test to check for giardia
- String test (rarely performed)
Treatment
If there are no symptoms or only mild symptoms, no treatment may be needed. Some infections go away on their own within a few weeks.
Medicines may be used for:
- Severe symptoms or symptoms that do not go away
- People who work in a daycare center or nursing home, to reduce the spread of disease
Antibiotic treatment is successful for most people. These include tinidazole, nitazoxanide or metronidazole. A change in the type of antibiotic will be tried if symptoms do not go away. Side effects from some of the medicines used to treat giardia are:
- Metallic taste in the mouth
- Nausea
- Severe reaction to alcohol
In most pregnant women, treatment should not start until after delivery. Some drugs used to treat the infection can be harmful to the unborn baby.
Possible Complications
These complications can occur:
- Dehydration (loss of water and other fluids in the body)
- Malabsorption (inadequate absorption of nutrients from the intestinal tract)
- Weight loss
When to Contact a Medical Professional
Contact your health care provider if:
- Diarrhea or other symptoms last for more than 14 days
- You have blood in your stool
- You are dehydrated
Prevention
Purify all stream, pond, river, lake, or well water before drinking it. Use methods such as boiling, filtration, or iodine treatment.
Workers in daycare centers or institutions should use good handwashing and hygiene techniques when moving from child to child or person to person.
Safer sexual practices may decrease the risk for getting or spreading giardiasis. People practicing anal sex should be especially careful.
Peel or wash fresh fruits and vegetables before eating them.
References
Goering RV, Dockrell HM, Zuckerman M, Chiodini PL. Gastrointestinal tract infections. In: Goering RV, Dockrell HM, Zuckerman M, Chiodini PL, eds. Mims' Medical Microbiology and Immunology. 6th ed. Philadelphia, PA: Elsevier; 2019:chap 23.
Melia JMP, Sears CL. Infectious enteritis and proctocolitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 110.
Nash TE, Hill DR. Giardiasis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 330.
Nash TE, Bartelt LA. Giardia lamblia. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 279.
Version Info
Last reviewed on: 3/10/2022
Reviewed by: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
