Cervical intraepithelial neoplasia - dysplasia; CIN - dysplasia; Precancerous changes of the cervix - dysplasia; Cervical cancer - dysplasia; Squamous intraepithelial lesion - dysplasia; LSIL - dysplasia; HSIL - dysplasia; Low-grade dysplasia; High-grade dysplasia; Carcinoma in situ - dysplasia; CIS - dysplasia; ASCUS - dysplasia; Atypical glandular cells - dysplasia; AGUS - dysplasia; Atypical squamous cells - dysplasia; Pap smear - dysplasia; HPV - dysplasia; Human papilloma virus - dysplasia; Cervix - dysplasia; Colposcopy - dysplasia
Cervical dysplasia refers to abnormal changes in the cells on the surface of the cervix. The cervix is the lower part of the uterus (womb) that opens at the top of the vagina.
The changes are not cancer. But they are considered to be precancerous. This means they can lead to cancer of the cervix if not treated.
Cervical dysplasia can develop at any age. However, follow up and treatment will depend on your age.
Most often, cervical dysplasia is caused by the human papillomavirus (HPV). HPV is a common virus that is spread through sexual contact. There are many types of HPV. Some types lead to cervical dysplasia or cancer. Other types of HPV can cause genital warts.
The following may increase your risk for cervical dysplasia:
Most of the time, there are no symptoms.
You will have a pelvic exam.
Cervical dysplasia that is seen on a Pap smear is called squamous intraepithelial lesion (SIL). On the Pap smear report, these changes will be described as:
You will need more tests if a Pap smear shows abnormal cells or cervical dysplasia. If the changes were mild, follow-up Pap smears may be all that is needed.
A biopsy to confirm the condition is often needed, however. This may be done using colposcopy-directed biopsy. A colposcopy is a procedure performed in your health care provider's office. Any areas of concern will be biopsied. The biopsies are very small and most women feel only a small cramp.
Dysplasia that is seen on a biopsy of the cervix is called cervical intraepithelial neoplasia (CIN). It is grouped into 3 categories:
Some strains of HPV are known to cause cervical cancer. An HPV DNA test can identify the high-risk types of HPV linked to this cancer. This test may be done:
Treatment depends on the degree of dysplasia. Mild dysplasia (LSIL or CIN I) may go away without treatment.
Treatment for moderate-to-severe dysplasia or mild dysplasia that does not go away may include:
If you have had dysplasia, you will need to have repeat exams every 12 months or as recommended by your provider.
Make sure to get the HPV vaccine when it is offered to you. This vaccine prevents many cervical cancers.
Early diagnosis and prompt treatment cures most cases of cervical dysplasia. However, the condition may return.
Without treatment, severe cervical dysplasia may change into cervical cancer.
Call your provider if your age is 21 or older and you have never had a pelvic exam and Pap smear.
Ask your provider about the HPV vaccine. Girls who receive this vaccine before they become sexually active reduce their chance of getting cervical cancer.
You can reduce your risk of developing cervical dysplasia by taking the following steps:
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Last reviewed on: 4/5/2016
Reviewed by: Irina Burd, MD, PhD, Associate Professor of Gynecology and Obstetrics at Johns Hopkins University School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.