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"Researchers Identify Metabolic Cycles In Baby Teeth Linked To ADHD And Autism In Children"

  • Medical Xpress
  • New York, NY
  • (September 26, 2019)

Mount Sinai researchers have identified elemental signatures in baby teeth that are unique to attention-deficit/hyperactivity disorder, autism spectrum disorder, and cases when both neurodevelopment conditions are present, which suggests that the metabolic regulation of nutrients and toxins play a role in these diseases, according to a study published in Translational Psychiatry. “Environmental epidemiologists typically study exposure to essential and toxic elements by examining how much of a given element a child was exposed to, but our work indicates that the way a child metabolizes environmental exposures is essential to healthy neurodevelopment,” said Paul Curtin, PhD, assistant professor of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai. He added, “The discovery that autism spectrum disorder, attention-deficit/hyperactivity disorder, and the combined presentation of autism and ADHD each have a unique metabolic signature can inform future studies on what might cause the disorders. It could help us determine the pathways implicated in the different diseases, which, in turn, could inform the development of treatment and prevention strategies.”

— Paul C. Curtin, PhD, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai

— Christine Austin, PhD, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai

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Additional coverage: Medpage Today