Mount Sinai, Pfizer Renew Research Collaboration, Building on Strong Foundation
The Icahn School of Medicine at Mount Sinai and Pfizer Inc.’s Centers for Therapeutic Innovation (CTI) recently announced the renewal of an agreement designed to identify and advance new drug candidates linked to major diseases, such as cancer, rheumatoid arthritis, Crohn’s disease, colitis, heart failure, Alzheimer’s disease, and cystic fibrosis.
In 2010, Mount Sinai became one of the first academic medical centers to enter into a collaboration with CTI, a Pfizer research group with the aim of speeding novel drugs toward approval for use in the clinic. The collaboration allows Mount Sinai investigators to submit research proposals to CTI, and for CTI to provide funding and drug development expertise, which can facilitate the development of new therapies. To date, five Mount Sinai projects have been funded through this process, focusing mainly in the areas of diabetes, autoimmune disease and cancer.
Project proposals are chosen through a rigorous vetting process by a steering committee composed of leading Pfizer and Mount Sinai scientists. Funded projects must have the strong potential to address an unmet medical need. Resulting research collaborations complement the biological expertise at Mount Sinai with Pfizer’s drug discovery and development capabilities, including the ability to create antibodies and small-molecules.
“Best–in-class translational research rarely occurs in a vacuum. Mount Sinai is dedicated to bringing therapeutics from the bench to the bedside, to improve health outcomes. Capitalizing on the synergies between industry and academic capabilities brings us closer to this goal,” said Erik Lium, PhD, Senior Vice President of Mount Sinai Innovation Partners (MSIP), the technology development and commercialization arm of Mount Sinai.
According to CTI’s Chief Scientific Officer, Anthony J. Coyle, PhD, “CTI and Mount Sinai have a long-standing and exceptional track record of research collaboration aimed at bringing early-stage medical discoveries towards the clinic. This renewed commitment will further enhance our alliance.”
MSIP facilitates the real-world application and commercialization of Mount Sinai discoveries and the development of research partnerships with industry. MSIP is responsible for the full spectrum of commercialization activities required to bring the Icahn School of Medicine’s inventions to life. These activities include evaluating, patenting, marketing, and licensing new technologies, while also engaging commercial and non-profit relationships for sponsored research, material transfer, and confidentiality. For more information, visit www.ip.mountsinai.org.
About the Mount Sinai Health System
The Mount Sinai Health System is an integrated health system committed to providing distinguished care, conducting transformative research, and advancing biomedical education. Structured around seven hospital campuses and a single medical school, the Health System has an extensive ambulatory network and a range of inpatient and outpatient services—from community-based facilities to tertiary and quaternary care.
The System includes approximately 7,100 primary and specialty care physicians; 12 joint-venture ambulatory surgery centers; more than 140 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers. Physicians are affiliated with the renowned Icahn School of Medicine at Mount Sinai, which is ranked among the highest in the nation in National Institutes of Health funding per investigator. The Mount Sinai Hospital is in the "Honor Roll" of best hospitals in America, ranked No. 15 nationally in the 2016-2017 "Best Hospitals" issue of U.S. News & World Report. The Mount Sinai Hospital is also ranked as one of the nation's top 20 hospitals in Geriatrics, Gastroenterology/GI Surgery, Cardiology/Heart Surgery, Diabetes/Endocrinology, Nephrology, Neurology/Neurosurgery, and Ear, Nose & Throat, and is in the top 50 in four other specialties. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 10 nationally for Ophthalmology, while Mount Sinai Beth Israel, Mount Sinai St. Luke's, and Mount Sinai West are ranked regionally. Mount Sinai's Kravis Children's Hospital is ranked in seven out of ten pediatric specialties by U.S. News & World Report in "Best Children's Hospitals."