"Researchers Identify the Tactic Dengue Virus Uses to Delay Triggering Immune Response"
Using the dengue virus (DENV) as a model, researchers from the Icahn School of Medicine at Mount Sinai have identified the "viral sensor" that initiates an immune response and have also described how the virus counteracts this mechanism and evades immune detection. "Our study shows how dengue virus, which affects people around the globe, employs multiple techniques to avoid detection,” said Ana Fernandez-Sesma, PhD, a professor of microbiology and infectious diseases at the Icahn School of Medicine at Mount Sinai. “We shed light on the mechanisms cells use to recognize the traces of viral infection within a cell and the methods viruses have acquired to obstruct them. It is this recognition that eventually leads to an immune response."
- Ana Fernandez-Sesma, PhD, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai