News-Medical.net - "Repeated Cocaine Use Can Increase Individual's Risk Of Mood Disorders"

 – August 24, 2011 /Press Release/  –– 

A new study finds that repeated cocaine use increases the severity of depressive-like responses in a mouse model of depression and identifies a mechanism that underlies this cocaine-induced vulnerability. The research, published by Cell Press in the August 25 issue of the journal Neuron, may guide development of new treatments for mood disorders associated with substance abuse. "Clinical evidence shows that substance abuse can increase an individual's risk for a mood disorder," explains senior study author, Dr. Eric Nestler from Mount Sinai School of Medicine. Learn more.