News-Medical.net - "HIPK2 Regulator Protein Plays a Crucial Role In Kidney Fibrosis"

 – March 12, 2012 /Press Release/  –– 

Researchers from Mount Sinai School of Medicine have identified a regulator protein that plays a crucial role in kidney fibrosis, a condition that leads to kidney failure. The research is published in the March 11 issue of Nature Medicine. Led by John Ci-jiang He, MD, PhD and Avi Ma'ayan, PhD at Mount Sinai School of Medicine, the research team studied three mouse models of kidney fibrosis: one group contained HIV viral proteins incorporated into their genome; the second was injected with a high dose of folic acid; in the third, kidney filtration was blocked in one kidney. Learn more