Photo of Yu-Feng Chan

Yu-Feng Y Chan, MD, PhD Email Yu-Feng Chan

    • Positions
    • ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
    • ASSOCIATE PROFESSOR | Emergency Medicine
    • Language
    • English

Dr. Yvonne Chan is a board-certified Emergency Medicine physician with a PhD in clinical research as well as experience in mobile health applications, pharmacogenomics, clinical trials and patient education.

During Dr. Chan’s 7 years at New Jersey Medical School, she served as the Associate then Research Director for the EM residency and medical student EM electives as well as the fieldwork site supervisor for the MD/MPH students. Dr. Chan was the principal investigator for the Stroke Education Center in the Emergency Department Waiting Room studies and was also a co-investigator for a CDC HIV Counseling, Testing, and Referral Services project.

In 2008, Dr. Chan took an EM faculty position at Icahn School of Medicine at Mount Sinai to pursue formal research training. After a two year NIH/National Institute of Neurological Disorders and Stroke (NINDS) T32 Post-doctoral Cerebrovascular Research Fellowship at Sinai, she was awarded the NIH Institutional KL2 Clinical and Translational Research Career Development Award and received her PhD in Clinical Research from the Mount Sinai Graduate School of Biological Sciences. Dr. Chan’s dissertation was on the Pharmacogenetics of clopidogrel in the Mount Sinai Biobank Cohort. During her training, she was the co-investigator of three NINDS clinical trials: the ‘Platelet-Oriented Inhibition in New TIA and minor ischemic stroke (POINT),  Tenecteplase (TNK) in acute ischemic stroke, and the Discharge Education Strategies for Reduction of Vascular Events (DESERVE) trials. In addition, she collaborated with the Institute of Personalized Medicine faculty on the CLIPMERGE (CLinical Implementation of Personalized Medicine through Electronic Health Records and Genomics) project. Currently, she is a co-investigator on the Patients with Mild Stroke: Rapidly Improving Symptoms and Neurologic Deficits (PRISMS) Trial.

In 2014, Dr. Chan joined the Institute of Genomics and Multiscale Biology as the Director of Personalized Medicine (PM) and Digital Health (DH). Her role is to lead the Institute in clinical trial study design, execution, and management of all DH and PM related clinical trials and initiatives conducted at the institute. She also serves as the collaborator and client liaison for these projects.


Research Interests:

·         Mobile Health Applications

·         Personalized Medicine

·         Clinical Trials

·         Pharmacogenomics

·         Stroke genomics

·         Patient education

Nationally, Dr. Chan was elected as Chair of the Society of Academic Emergency Medicine's Neurological Interest Group. She was an American College of Emergency Medicine representative for the NINDS Brain Attack Coalition Stroke Messaging Committee and a participant at the NIH Roundtable on Opportunities to advance Research on Neurological and Mental Health Emergencies. She is a member of the American Stroke Association Stroke Committees as well as the International Stroke Genetics Consortium (ISGC). In addition, she is a writing group member of the American Heart Association Guidelines for CPR and Emergency Cardiovascular Care as well as the ISGC Protocols and Guidelines.

Within the Mount Sinai system, Dr. Chan chaired the Stroke Arrivals Committee and serves as the Emergency Medicine liaison for the Comprehensive Stroke Center as well as the Stroke Emergency Medicine Combined Conference.


Clinical Focus


PhD, Icahn School of Medicine