
Thomas Marron, MD, PhD

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- Position
- ASSOCIATE PROFESSOR | Medicine, Hematology and Medical Oncology
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- Specialties
- Cancer (Oncology)
- Hematology-Oncology
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- Language
- English
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- Hospital Affiliations
- Mount Sinai Beth Israel
- Mount Sinai Morningside and Mount Sinai West
- The Mount Sinai Hospital
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- Phone
- Ruttenberg Treatment Center 212-241-6756 212-241-6756
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Ruttenberg Treatment Center
1470 Madison Avenue
3rd Floor
New York, NY 10029
Phone: 212-241-6756212-241-6756
Thomas Marron, MD, PhD, is the Director of the Early Phase Trials Unit (EPTU) at The Tisch Cancer Institute and Associate Professor of Medicine (Hematology and Medical Oncology) at the Icahn School of Medicine at Mount Sinai. He is a Medical Oncologist, and holds a PhD in Immunology; his research focuses on development of cancer immunotherapies.
EPTU focuses on Phase 1 and Phase 2 multi-histology clinical trials developing novel agents and combinations of new and old agents that are being tried across solid tumor types. Dr. Marron’s focus is on the immunotherapy space, with particular focus on novel immunomodulatory agents and cancer vaccine strategies.
As a member of the Center for Thoracic Oncology, Dr. Marron treats thoracic malignancies, including non-small cell lung cancer, small cell lung cancer, and malignant pleural mesothelioma. He leads numerous industry-sponsored as well as investigator-initiated clinical trials for thoracic malignancies as well hepatocellular carcinoma (liver cancer).
As a member of The Tisch Cancer Institute and the Precision Immunology Institute, Dr. Marron works closely with basic scientists across the Mount Sinai Health System, translating preclinical findings into clinical advances. He also leads The neoAdjuvant Research Group to Evaluate Therapeutics (TARGET) which is housed in EPTU and is a large cross-disciplinary collaborative translational research program focused on clinical trials for multiple types of cancer in which patients receive novel therapies prior to surgery. These neoadjuvant trials are often called “window-of-opportunity” trials given the brief nature of the pre-surgical intervention, and opportunity to learn a great deal about novel agent’s mechanisms of action in humans. The goal of these trials is to decrease the likelihood that cancer will return after surgery; in parallel, they support deep interrogation of the effect of new and standard therapies on the tumor immune microenvironment at the single-cell level. Further, the trials enable Dr. Marron and collaborators to define combination approaches that optimize response rates and the durability of novel immune-based therapies, while minimizing toxicity to patients.
Clinical Focus
Education
MD,PHD, Mount Sinai School of Medicine
Residency, Internal Medicine
Mount Sinai Hosptial
Fellowship, Medical Oncology
Mount Sinai Hospital
Language
English
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Marron during 2021 and/or 2022. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting:
- Regeneron Pharmaceuticals
- surface
Industry-Sponsored Lectures: MSSM faculty occasionally give lectures at events sponsored by industry, but only if the events are free of any marketing purpose
- AstraZeneca
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
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