Terry F Davies, MD Email Terry Davies
- PROFESSOR | Medicine, Endocrinology, Diabetes and Bone Disease
- PROFESSOR | Obstetrics, Gynecology and Reproductive Science
- Endocrine, Diabetes and Bone Diseases
- Hospital Affiliations
- The Mount Sinai Hospital
- Mount Sinai Beth Israel
Terry Francis Davies is the Florence and Theodore Baumritter Professor of Medicine at the Mount Sinai School of Medicine in New York and Director of their Division of Endocrinology and Metabolism at the James J. Peters VA Medical Center. Dr. Davies was trained in the UK, at the University of Newcastle upon Tyne but after training at the National Institutes of Health in Bethesda, MD, has spent most of his career in New York at the Mount Sinai School of Medicine. He has a long and distinguished record of significant contributions to our understanding of endocrine physiology and pathology having published over 400 peer reviewed scientific papers mostly in the area of thyroid disease at both a basic level, in the areas of immunology and genetics, and in the clinical arena in the area of autoimmune thyroid disease and pregnancy. Although Dr. Davies, as a clinician, is always included in the lists of New York's Best Doctors, the Davies Laboratory remains one of our pre-eminent sites for autoimmune thyroid disease research as evidenced by his extensive support from the National Institutes of Health. Dr. Davies has received many honors in his career, is a member of the American Association of Physicians and is the President-Elect of the American Thyroid Association. Dr. Davies was recently chosen by Women's Health as the pre-eminent Endocrinologist for women in New York City.
- Doppler Ultrasound
- Paget's Disease Of Bone
- Thyroid Cancer
- Vitamin D Deficiency
Autoimmunity, Genetics, Immunology, Knockout Mice, Receptors, Stem Cells, T Cells, Thyroid
Multi-Disciplinary Training Area
Pharmacology and Therapeutics Discovery [PTD]
MBBS, University of Newcastle-Upon-Tyne
, National Institute of Health
MD, University of New Castle-Upon-Tyne
Residency, Internal Medicine
University of Newcastle-Upon-Tyne
University of Newcastle-Upon-Tyne
National Institutes of Health
New York Magazine
American Thyroid Association
International Autoimmunity Conference, Porto, Portugal
Honorary President for Life
United States Friends of Newcastle University
Veterans Affairs Merit Award
International Autoimmunity Congress, Sorrento, Italy
Canadian Society for Endocrinology, Toronto
German Endocrine Society, Muenster
4th International Congress on Autoimmunity, Budapest, Hungary
Australian Endocrine Society, Melbourne
Thyroid Foundation of America
Specific Clinical/Research Interest:
Mechanisms in autoimmune disease with an emphasis on autoimmune thyroid disease
Postdoctoral Fellows: Marco Agote-Robertson PhD, Sayed Moshad PhD, Chris Michalek MD, PhD, Risheng Ma, PhD
Research Personnel: Rauf Latif PhD, Xiaoming Yin PhD, Zhong Yao
Summary of Research Studies:
Research areas of emphasis include: The TSH receptor molecule: This is the major autoantigen in human Graves' disease which is a form of autoimmune hyperthyroidism. The TSHR remains an elusive quarry ten years after it was cloned becsue of its highly complex processing. Our emphasis is on the post translational processing events involved with multimerization and intramolecular cleavage of the TSHR and its status in lipid rafts. Complex Genetics: The aim of this research has been to detect the susceptibility genes for autoimmune thyroid disease using genome screening of informative families with Graves' disease and/or Hashimoto's thyroiditis. Our group has experience in the analysis of families with these disorders and we have a large collection of well characterized families to study. Currently, our areas of emphasis are on individual susceptibility genes. In particular the TSH receptor intron 1 region where we have identified miRNAs close to associated SNPs and the role of epigenetics(using X chromosome inactivation) in disease susceptibility and its influence on the autoimmune response. Animal models of autoimmune thyroid disease: We have developed models of hyperthyroid mice immunized with an adenoviral vector incorporating the TSH receptor as a model for Graves' disease. These studies involve the development and characterization of unique monoclonal antibodies to the TSH receptor with thyroid stimulating activity with an emphasis on epitope characterization and signal transduction.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Davies during 2019 and/or 2020. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Service on Board of Directors: Service in a fiduciary capacity, such as an officer or director, for the following companies:
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