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Stephen Scelsa, MD Email Stephen Scelsa

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Mount Sinai Doctors ?
    • Position
    • PROFESSOR | Neurology
    • Specialties
    • Neurology
    • Electrodiagnostic Medicine
    • Language
    • English
    • Hospital Affiliations
    • The Mount Sinai Hospital
    • Mount Sinai Brooklyn
    • Mount Sinai Morningside and Mount Sinai West
    • Mount Sinai Beth Israel

Book an Appointment - Stephen Scelsa, MD

I am a  neurologist and  neuromuscular specialist with expertise in Amyotrophic Lateral Sclerosis (ALS) clinical care and trials.  I am the co-founder and Director of the Beth Israel Medical Center/ALS Association NY Chapter ALS Center that  was created in 1997.  Since 2003, the center has gained national recognition for participation in ALS clinical trials. I have access to a large population of patients with Amyotrophic Lateral Sclerosis. We became part of the Mount Sinai Health System in 2013. We follow 120 patients at any given time. I am an active member of NEALS, the North Eastern ALS Consortium. I have a strong interest in conducting clinical trials in ALS and other neuromuscular diseases.

At Mount Sinai Beth Israel, we conducted an investigator initiated phase1/2 trial of indinavir in ALS, in collaboration with Columbia University Medical Center. I was the principle investigator.

Our center has also conducted a controlled study of reverse transcriptase detection in the serum and CSF of HIV negative, sporadic ALS patients.

I received 4 NIH consortium grants for clinical trials in ALS patients. The most recent was a phase 3 clinical trial of ceftriaxone in ALS, sponsored by Massachusetts General Medical Center and the NIH.

We are also participating in a new study to validate a new functional scale for PLS (primary lateral sclerosis) with Dr Mitsumoto at Columbia University. PLS is a neglected disease in clinical trials.  I am very interested in developing new clinical trials in PLS and this project provides a great opportunity.

We conducted multiple clinical trials as a multi-site PI in NIH consortium grants, have participated in the first round of NeuroNext with our prior academic affiliation (Albert Einstein College of Medicine, NY), and have a reliance agreement with NEALS (Northeast ALS Consortium) and Massachusetts General, Boston, MA to assist in fast tracking phase 2 clinical trials that are part of NEALS (similar to NeuroNEXT), including the ongoing Amylyx pharmaceuticals Centaur study.

We are  currently completing a phase 3  Orien pharmaceutical study of Levosimendan in the treatment of ALS.

We are participating in the ALS arm of the Mount Sinai Hospital’s NeuroNEXT grant. 

We also studying ocular motor dysfunction in patients with ALS and other forms of motor neuron disease.

We are participating in NIH consortium grants studying Agrin and LRP for antibodies in double negative myasthenia gravis.

I offer telemedicine appointments when appropriate.  Please call my office to schedule a video visit.

Dr. Scelsa is registered to provide telehealth services in Florida.

Curriculum Vitae


Am Board of Electrodiagnostic Medicine
Neurology, American Board of Psychiatry and Neurology

Clinical Focus

Research Topics

Amyotrophic Lateral Sclerosis


MD, S.U.N.Y., Health Science Center

Internship, Internal Medicine
Montefiore Medical Center

Residency, Neurology
Albert Einstein College of Medicine

Fellowship, Neurology
Albert Einstein College of Medicine



Download the CV