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Matthew A Levin, MD Email Matthew Levin

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Mount Sinai Doctors ?
    • Positions
    • ASSOCIATE PROFESSOR | Anesthesiology, Perioperative & Pain Medicine
    • ASSOCIATE PROFESSOR | Genetics and Genomic Sciences
    • Specialty
    • Anesthesiology
    • Language
    • English
    • Hospital Affiliation
    • The Mount Sinai Hospital

Dr. Levin is a Board Certified Cardiac Anesthesiologist, Board Certified Clinical Informaticist, Director of Research Informatics for the Department of Anesthesiology, Perioperative & Pain Medicine, and Director of the Clinical Data Science Team for the Mount Sinai Health System. He also holds a joint appointment in the Department of Genetics and Genomics Sciences and collaborates with the Icahn Institute for Data Science and Genomic Technology. Dr. Levin began his career by working for five years in Silicon Valley and the software industry during the dot-com boom. He then changed careers to pursue medicine, but never lost his passion for technology. Dr. Levin is excited to be bringing the latest innovations in systems architecture, machine learning and big data into the healthcare arena in order to improve patient care and save lives. He created and directs the Department of Anesthesiology's large perioperative data warehouse, which contains detailed demographic, physiologic, and medication data for over 900,000 anesthetic cases. As Director of the Health System Clinical Data Science Team, he has been leading the initiative to build a streaming data science pipeline that enables the deployment of real-time machine learning algorithms to provide next-generation decision support and alerting to front line clinicians. 

Dr. Levin's clinical research interest is in understanding risk factors for morbidity and mortality in perioperative period, with particular focus on intraoperative physiology and hemodynamics. I have published extensively in this area. Through his multi-disciplinary collaborations with other researchers in the Icahn School of Medicine, he is pushing the boundaries of perioperative research in order to answer previously un-addressable questions on the phenotype and genotype of the response to anesthetic and surgical stress.  Dr. Levin is affiliated with The Charles Bronfman Institute for Personalized Medicine and collaborates closely with fellow IPM member Dr. Eimear Kenny.  Together they were awarded a prestigious two year starter grant (2015-2017) from the Society of Cardiovascular Anesthesiologists to investigate the Genomics of Vasoplegia, a condition of profound, persistent hypotension sometimes seen after cardiopulmonary bypass.  Dr. Levin's 2014 article "Low intraoperative tidal volume ventilation with minimal PEEP is associated with increased mortality" was recently recognized as the most cited article from 2013-2014 in the British Journal of Anaesthesia, contributing to the BJA's increase in impact factor to 5.616.


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American Board of Preventive Medicine
American Board of Anesthesiology

Research Topics

Anesthesia, Bioinformatics, Cardiovascular, Genomics


MD, Mount Sinai School of Medicine

BS, Massachusetts Institute of Technology

Internship, Surgery
Lenox Hill Hospital

Residency, Anesthesiology
Mount Sinai Hospital

Fellowship, Cardiothoracic Anes.
Mount Sinai Hospital



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