Li Wang, PhD Email Li Wang
- ASSISTANT PROFESSOR | Genetics and Genomic Sciences
Li Wang works on developing and applying computational methodologies to address questions in precision medicine. Dr Li Wang has a multi-disciplinary background in biology, computer science, statistics and computational biology. She got her PhD degree in computional biology from University of Southern california. She then joined the oncology department at Novartis Institute of Biomedical Research where she focused in the Cancer Cell Line Encyclopedia project, predicting drug sensitivity using genomic features, e.g., mutation, copy number, mRNA transcription, etc., Many the predictive models have been validated in primary xenograft models and translated into guidance in clinical trials. After joining Department of Genomics and Genetics at Mount Sinai, she is mostly interested in the field of cancer immunology and immunotherapy. She developed blood gene expression based prognostic models for prostate cancer and won a young investigator award from Prostate Cancer Foundation. She published several computational methodology papers to analyze and deconvolve mixed blood gene expression and bulky tumor expression data. Her recent study in the tumor microenvironment of bladder cancer (published in Nature communication) brought new insights into the resistant mechanisms to PD-L1 blockade. She also served as director of big data science at Sema4, a Mount Sinai adventure.
BS, University of Science and Technology of China
MS, University of Southern California
PhD, University of Southern California
Developing statistical models to computationally dissecting tissue heterogeneity.
Understand immune systems by integrating Omics data including single cell sequencing, with applications to cancer immunology, immunotherapy and infectious diseases.
Network and Integrative systems biology
Developing network-based integrative computational algorithms to understand biological systems and disease mechanism.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Wang during 2021 and/or 2022. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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