Photo of Li Wang

Li Wang, PhD Email Li Wang

    • Position
    • ASSISTANT PROFESSOR | Genetics and Genomic Sciences
    • Language
    • English

Li Wang works on developing and applying computational methodologies to address questions in precision medicine. Dr Li Wang has a multi-disciplinary background in biology, computer science, statistics and computational biology. She got her PhD degree in computional biology from University of Southern california. She then joined the oncology department at Novartis Institute of Biomedical Research where she focused in the Cancer Cell Line Encyclopedia project, predicting drug sensitivity using genomic features, e.g., mutation, copy number, mRNA transcription, etc., Many the predictive models have been validated in primary xenograft models and translated into guidance in clinical trials. After joining Department of Genomics and Genetics at Mount Sinai, she is mostly interested in the field of cancer immunology and immunotherapy. She developed blood gene expression based prognostic models for prostate cancer and won a young investigator award from Prostate Cancer Foundation. She published several computational methodology papers to analyze and deconvolve mixed blood gene expression and bulky tumor expression data. Her recent study in the tumor microenvironment of bladder cancer (published in Nature communication) brought new insights into the resistant mechanisms to PD-L1 blockade. She also served as director of big data science at Sema4, a Mount Sinai adventure.

 

Research Topics

Bioinformatics, Immunology

Education

BS, University of Science and Technology of China

MS, University of Southern California

PhD, University of Southern California

Language

English