Judy H Cho, MD Email Judy Cho
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- Positions
- DIRECTOR, INSTITUTE FOR PERSONALIZED MEDICINE
- SENIOR ASSOCIATE DEAN FOR PRECISION MEDICINE
- PROFESSOR | Genetics and Genomic Sciences
- PROFESSOR | Medicine, Gastroenterology
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- Language
- English
Dr. Judy Cho earned her B.A. and M.D. at Ohio State University, where she graduated summa cum laude, and was a member of Phi Beta Kappa and AOA. After postdoctoral training at Northwestern University, she became a faculty member at the University of Chicago. In 2004, she was recruited as Associate Professor to Yale University where she became the Henry J. and Joan W. Binder Professor of Medicine, Genetics and Pediatrics. Dr. Cho was recruited in 2013 to the Icahn School of Medicine at Mount Sinai as the Ward-Coleman Professor of Translational Genetics and Medicine, Vice-Chair of Translational Genetics and Gastroenterology and Director of Ceported. She is currently the Principal Investigator and chair of the Steering Committee of the NIDDK IBD Genetics Consortium and is a member of the NIDDK Advisory Council. She is also on the council of the American Society of Clinical Investigation (ASCI) and is active in the Crohn’s and Colitis Foundation and the American Gastroenterology Association, serving on its Research Policy Committee. Dr. Cho has extensive experience in defining genetic factors underlying susceptibility to inflammatory bowel disease (IBD). She was the senior investigator reporting the initial associations of NOD2 to Crohn’s disease, the IBD GWAS first identifying the interleukin 23 receptor associations, and most recently, the IBD Immunochip manuscript identifying 163 IBD-assoicated loci. She is particularly interested in defining the genetic architecture underlying the higher IBD prevalence among Ashkenazi Jews. Her laboratory is interested in defining the genetic architecture underlying differentiation of distinct immune cell subsets, differences in epigenetic landscape of immune cell subsets, and their effects in IBD. Her research has been supported by various NIH institutes (NIDDK, NCRR, NIAID, and NIGMS), the Crohn’s and Colitis Foundation of America, and The Eli and Edythe L. Broad Foundation and the Burroughs Wellcome Fund. Because Dr. Cho has served as Principal Investigator for the DCC of the 7 center NIDDK IBD Genetics Consortium (IBDGC) for the past twelve years, she also has extensive experience in leading multi-investigator research groups. During the present period of funding, the IBDGC has been charged with developing new collaborations in order to define the functional effects of IBD-associated variants. In this capacity, they have supported a variety of ancillary R01 applications from multi-disciplinary collaborators (epigeneticists, immunologists, systems biologists) in order to fully leverage the extensive IBD genetic discoveries.
Dr. Cho works with the Department of Genetics and Genomic Sciences and Gastroenterology as well as the Icahn Institute of Data Science and Genomic Technology.
Multi-Disciplinary Training Areas
Genetics and Data Science [GDS], Immunology [IMM], Pharmacology and Therapeutics Discovery [PTD]
Education
BA, Ohio State University
MD, Ohio State University College of Medicine
Postdoctoral training, Northwestern University
Postdoctoral training, Northwestern University
Postdoctoral training, University of Chicago
Language
English
2014
Member, American Association of Physicians (AAP)
2014
CCFA Scientific Achievement in IBD Basic Science Award
2013
Clinical Research Forum, Top 10 Research Achievements Award 2013
2012
Member, Research Policy Committee, American Gastroenterological Association
2011
NIDDK Advisory Council
2010
NIH Wednesday Afternoon Lecture seminar
2008
Member, American Society of Clinical Investigation Council 2008-2011
2007
Editorial Board, American Journal of Human Genetics
2007
Editorial Board, Human Molecular Genetics
2005
Member, American Society of Clinical Investigation
2004
Member, Genetics of Health and Disease study section
Genetics and Environmental Factors associated with Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD) is a group of conditions of the gastrointestinal tract with chronic or recurring immune response and inflammation. The two most common types are Ulcerative Colitis (UC) and Crohn’s Disease (CD). Other types of IBD include Indeterminate Colitis (IC) and Inflammatory Bowel Disease Unclassified (IBDU). These are considered more as temporary diagnoses when the difference between UC and CD cannot be determined at the time of presentation. In the United States, about 1 – 1.3 million people suffer from IBD. Although IBD can affect people of all ages, the peak age of onset is between 15 and 30 years old. The exact cause of IBD is not entirely understood, but it is known to involve an interaction between genes, the immune system, and environmental factors.
Click here to visit Dr. Cho's Lab website.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr.Cho did not report having any of the following types of financial relationships with industry during 2018 and/or 2019: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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