James F Sumowski, PhD
- ASSOCIATE PROFESSOR | Neurology
- ASSOCIATE PROFESSOR | Psychiatry
- Hospital Affiliation
- The Mount Sinai Hospital
- Corinne Goldsmith Dickinson Center for MS 212-241-6854 212-241-6854
James F. Sumowski, Ph.D. is an Associate Professor of Neurology at Mount Sinai and the clinical neuropsychologist at the Corinne Goldsmith Dickinson Center for Multiple Sclerosis (MS). Dr. Sumowski is an expert on cognition in persons with MS, and he introduced the concept of “reserve” against cognitive decline in MS: the observation that genetic and environmental factors can moderate deleterious effects of disease on functional outcomes (representative article: Sumowski et al., Neurology 2014). The Sumowski Laboratory works to advance understanding and improvement of functional outcomes. Toward this end, Dr. Sumowski is the PI of a large prospective National Institutes of Health (NIH / NICHD) R01 grant to identify modifiable risk and protective factors linked to cognitive decline, which will inform future interventions.
Dr. Sumowski is a leader in the field. He recently led an international group of MS experts toward a joint statement of knowledge gaps, obstacles, and research priorities for the field of cognition in persons with MS (Sumowski et al., Neurology 2018). In addition to outlining several specific recommendations for research and clinical practice, the statement highlights the critical need to develop testable and biologically plausible models of cognitive decline due to MS, which will lay the groundwork for much-needed evidence-based rehabilitation.
Dr. Sumowski is Co-Director of the Postdoctoral Fellowship in Clinical Neuropsychology and Clinical Research at Mount Sinai, which will prepare trainees for careers as clinician-researchers in academic medical center settings. He is also an Adjunct Professor at Teachers College, Columbia University, where he serves as dissertation mentor for Ph.D. candidates.
- Memory Disorder
- Multiple Sclerosis
- Neuropsychological testing
Cognitive Neuroscience, Memory, Multiple Sclerosis
BA, Seton Hall University
PhD, Columbia University
Long Island Jewish Medical Center
New Jersey Medical School - Rutgers University
Reserve against Cognitive Decline Due to Multiple Sclerosis
Cognitive decline is common among persons with neurologic diseases, including multiple sclerosis (MS); however, some persons are better able to withstand neurologic disease without difficulties in thinking or memory. Dr. Sumowski's research seeks to identify sources of "reserve" against cognitive decline in persons with MS. He has shown that persons with MS who lead more mentally-active lifestyles (e.g., reading, hobbies) are at lower risk for disease-related cognitive decline. Dr. Sumowski's current work seeks to identify a range of modifiable lifestyle factors contributing to reserve, with the goal of advancing primary prevention of cognitive difficulties due to MS.
Memory Treatments for Persons with Multiple Sclerosis
Memory deficits are among the most common cognitive difficulties experienced by persons with multiple sclerosis (MS), with negative consequences for employment and overall quality of life. There are currently no validated treatments for MS memory impairment. Dr. Sumowski has published early stage research investigating memory interventions through the use of cognitive strategies, lifestyle modifications, and pharmaceutical interventions. Dr. Sumowski is engaging in research to better understand the neural basis of memory deficits due to MS, which will inform the development of novel treatments with greater promise for success.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Sumowski during 2019 and/or 2020. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
- Biogen Idec
- Genzyme Corporation
Other activities: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- Teachers College Columbia University
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
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