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James L Ferrara, MD Email James Ferrara

Pediatric Hematology-Oncology
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Mount Sinai Doctors ?
    • Positions
    • PROFESSOR | Pediatrics
    • PROFESSOR | Medicine, Hematology and Medical Oncology
    • PROFESSOR | Oncological Sciences
    • Specialty
    • Pediatric Hematology-Oncology
    • Language
    • English
    • Hospital Affiliation
    • The Mount Sinai Hospital
Dr. James Ferrara is a physician-scientist whose clinical and research career has focused on the immunology of bone marrow transplantation (BMT), particularly its major complication graft-versus-host-disease (GVHD). Using trailblazing proteomic techniques, his team has identified and validated unexpected biomarkers for skin, gut and steroid-resistant GVHD. He has created exceptionally large and informative biorepositories and then mined them to meld these biomarkers into the first algorithm that predicts response to treatment and that can guide GVHD therapy. Dr. Ferrara’s pioneering mechanistic studies have illuminated unexpected interactions between the innate and adaptive immune systems and have led to both conceptual breakthroughs and the discovery of novel therapeutic targets. A superb clinician and world-class clinical investigator, his decades-long focus on GVHD has significant potential impact in making BMT safer and more effective for all patients.

Dr. Ferrara graduated Cum laude from Georgetown Medical School and then completed his pediatric residency and fellowship at Boston’s Children’s and the Dana-Farber Cancer Institute. After 19 years at he went to the University of Michigan to direct the combined adult and pediatric BMT program. The Icahn School of Medicine at Mout Sinai recruited Dr. Ferrara in 2014 to become the Ward-Coleman professor of Cancer medicine and to direct the Center for Translational Resarch in Hematologic Malignancies.

Clinical Focus

  • Acute Lymphoid Leukemia
  • Acute Myeloid Leukemia
  • Bone Marrow Transplantation
  • Bone Marrow Transplantation, Allogeneic
  • Bone Marrow Transplantation, Autologous
  • Hematologic Malignancies
  • Hematologic Malignancies, Pediatric
  • Leukemia
  • Leukemias, Pediatric
  • Lymphoma
  • Myelodysplastic Syndromes
  • Myelofibrosis
  • Myeloproliferative Disorders
  • Transplantation

Research Topics

Cytokines, Immunological Tolerance, Immunology, Inflammation, Stem Cells, Transplantation

Multi-Disciplinary Training Areas

Cancer Biology [CAB], Immunology [IMM]

Education

MD, Georgetown University

Internship, Pediatrics
Childrens Hospital of Boston

Residency, Pediatrics
Childrens Hospital of Boston

Fellowship, Ped. Hemo/Onco
Dana Farber Cancer Institute

Language

English