, Nuremberg General Hospital, University of ErIangen-Nuremberg
, Cabrini Medical Center
, Massachusetts General Hospital and Harvard Medical School
, National Cancer Institute, National Institutes of Health
MD, Friedrich-Alexander Universitat School of Medicine, Erlangen-Nurember
Genetics and Genomic Sciences [GGS]
Wang W, Wyckoff JB, Frohlich VC, Oleynikov Y, Huttelmaier S, Zavadil J, Cermak L, Bottinger EP, Singer RH, White J, Segall J, Condeelis JS. Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res 2002; 62: 6278-6288.
Yang YC, Piek E, Zavadil J, Xie D, Liang D, Heyer J, Pavlidis P, Kucherlapati R, Roberts AB, Bottinger EP. Hierarchical Model of Gene Regulation by TGF-B. Proc Natl Acad Sci USA 2003; 100(18): 10269-10274.
Nicolaou F, Teodoridis JM, Park H, Georgakis A, Farokhzad OC, Bottinger EP, Da Silva N, Rousselot P, Chomienne C, Ferenczi K, Arnaout MA, Shelley CS. CDllc gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras andjunD. Blood 2003 May 15; 101(10): 4033-4041.
Wang W, Wyckoff JB, Wang Y, Bottinger EP, Segall JE, Condeelis JS. Gene expression analysis on small numbers of invasive cells collected by chemotaxis from primary mammary tumors of the mouse. BMC Biotechnol 2003 Aug 12; 3(1): 13.
Liu X, Wen FQ, Kobayashi T, Abe S, Fang Q, Piek E, Bottinger EP, Roberts AB, Rennard SI. Smad3 mediates the TGF-beta-induced contraction of type I collagen gels by mouse embryo ibroblasts. Cell Motil Cvtoskeleton 2003 Mar; 54(3): 248-253.
Yoo J, Ghiassi M, Jirmanova L, Balliet AG, Hoffman B, Fomace Jr AJ, Liebermann DA, Bottinger EP, Roberts AB. TGF-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45B through p38 activation. J Biol Chem 2003 Oct 31; 278: 43001-43007.
Goswami S, Sheets NL, Zavadil J, Chauhan BK, Bottinger EP, Reddy VN, Kantorow M, Cvekl A. The spectrum and range of oxidative stress responses of human lens epithelial cells to H202 insult: a cDNA microarray study. Invest Ophthalmol Vis Sci 2003; 44(5): 2084-2093.
Susztak K, Bottinger EP, Novetsky A, Liang D, Zhu Y, Ciccone E, Wu D, McCue P, Sharma K. Molecular Profiling of Diabetic Mouse Kidneys Reveals Novel Genes Linked toGlomerular Disease. Diabetes 2004; 53(3): 784-794.
Petkov PM, Zavadil J, Goetz D, Chu T, Carver R, Rogler CE, Bottinger EP, Shafritz DA, Dabeva MD. Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using cDNA microarrays. Hepatology 2004 Mar; 39(3): 617-627.
Zavadil J, Cermak L, Soto-Nieves N, Bottinger EP. TGF-B /Smad3 co-activate HEY1 and Jagged 1/Notch 1 in Epithelial-to-Mesenchymal Transition. EMBO J 2004 Mar 10; 23(5): 1155-1165.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Bottinger during 2015 and/or 2016. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).
Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.
Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.