Brian Kopell, MD Email Brian Kopell
- PROFESSOR | Neurosurgery
- PROFESSOR | Psychiatry
- PROFESSOR | Neuroscience
- PROFESSOR | Neurology
- Hospital Affiliations
- Mount Sinai Beth Israel
- The Mount Sinai Hospital
- Mount Sinai Morningside and Mount Sinai West
- Center for Neuromodulation at Mount Sinai West 212-523-8340 212-523-8340
Dr. Brian Kopell is a Professor of Neurosurgery, Neurology, Psychiatry, and Neuroscience as well as Director of the Center for Neuromodulation at the Mount Sinai Health System. Dr. Kopell has pioneered the use of intraoperative imaging during Deep Brain Stimulation (DBS) cases to supplement the microelectrode recording typically done to make a procedure that is safer and quicker for patients. He has performed over 1,000 DBS procedures.
A graduate of the NYU School of Medicine, Dr. Kopell completed his residency at NYU Medical Center. He has undergone fellowship training in Functional and Restorative Neurosurgery at the Cleveland Clinic Foundation and the University of Zurich. He founded and has led the Restorative Neuroscience Program at the Medical College of Wisconsin (Milwaukee, WI) where his team performed over 400 DBS cases for movement disorders. Furthermore, Dr. Kopell has participated and has been principal investigator in several clinical trials of emerging neuromodulation technologies targeting disorders such as Parkinson's disease, tremor, tinnitus, Tourette's syndrome and major depression.
DBS is widely recognized as the gold standard treatment for patients with disabling motor symptoms from idiopathic Parkinson's disease, essential tremor, and dystonia that have become refractory to medical therapy. This neurosurgical procedure is available within a fully-integrated multidisciplinary program through the Mount Sinai Health System.
In the News: Dr. Brian Kopell discusses the results of neuromodulation in The New York Daily News feature, The Daily Checkup.
Follow the Center for Neuromodulation on Twitter: @MountSinaiDBS
- Benign Essential Tremor
- Cancer Pain Syndromes
- Complex Regional Pain Syndrome
- Deep Brain Stimulation (DBS)
- Facial Pain
- Failed Back Surgery Syndrome
- Hemifacial Spasm
- Obsessive-Compulsive Disorder
- Occipital Neuralgia
- Parkinson's Disease
- Tourette Syndrome
- Trigeminal Neuralgia
MD, New York University School of Medicine
NYU Medical Center
NYU Medical Center
Cleveland Clinic Foundation
Top Doctors - New York Metro Area
Voted as one of the best neurosurgeons in the New York Metro Area
Cortical Stimulation for Tinnitus
Cortical and Deep Brain Stimulation for Depression and Obsessive Compulsive Disorder
Intraoperative Image-Guidance for Deep Brain Stimulation
Electrophysiological Biomarkers to Optimize Deep Brain Stimulation for Depression
The Icahn School of Medicine at Mount Sinai is running a single-center experimental trial of deep brain stimulation (DBS) to the subcallosal cingulate region (Area 25) for treatment resistant depression (TRD). The goal of this study is to refine and optimize this treatment approach using a newly available neuromodulation system (the Medtronic Summit RC+S) that allows brain activity during ongoing therapeutic DBS to be recorded from the brain in real-time. This study will further define brain readouts that track depression recovery, providing novel strategies to monitor and guide treatment and device programming decisions in patients receiving DBS for TRD.
Participating Mount Sinai Programs:
- Depression and Anxiety Center for Discovery and Treatment (DAC)
- Center for Neuromodulation
- Nash Family Center for Advanced Circuit Therapeutics
For more information visit Mount Sinai Clinical Trials.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Kopell during 2020 and/or 2021. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
- Abbott Laboratories
- Abbott Neuromodulation
- ClearPoint Neuro
- Medtronic, Inc.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
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