Anne Schaefer, MD, PhD Email Anne Schaefer
- PROFESSOR | Neuroscience
- PROFESSOR | Psychiatry
Click here for more information on Dr. Schaefer's 2012 Director’s New Innovator Award from the National Institutes of Health (NIH).
Dr. Schaefer is an Associate Professor of Neuroscience and Psychiatry and a Seaver Fellow at the Friedman Brain Institute at Mount Sinai School of Medicine. She did her graduate studies at the Johannes Gutenberg University Mainz, the Charité University Berlin and The Rockefeller University in New York. In the fall of 2004 she joined Dr. Paul Greengard's Laboratory at The Rockefeller University where she completed her postdoctoral studies and was promoted to Research Associate in 2007 and Senior Research Associate in 2009. She joined the Friedman Brain Institute at Mount Sinai School of Medicine to start her own laboratory in 2011. Her research is focused on understanding how epigenetic mechanisms contribute to maintenance of specialized neuronal functions and their alteration during psychiatric and neurodegenerative diseases.
Anne Schaefer has been named a 2014 Kavli Frontiers of Science Fellow by the National Academy of Sciences (NAS). The Kavli program honors young scientists who are considered leaders in their fields and have made significant contributions to science. Jointly sponsored by the US National Academy of Sciences and The Kavli Foundation, the Kavli Frontiers of Science bring together some of the very best young scientists (under age 45) to discuss exciting advances and opportunities in their fields in a format that encourages informal collective, as well as one-on-one discussions among participants. Dr. Schaefer was invited to the Japanese-American Frontiers of Science ( JAFoS) Symposium that took place in Tokio in December 2014.
Visit Anne Schaefer's Laboratory of Brain Epigenetics for more information.
Basal Ganglia, Brain, Chromatin, Epigenetics, Genetics, Human Genetics and Genetic Disorders, Knockout Mice, Locomotion, Mental Retardation, Multiple Sclerosis
Multi-Disciplinary Training Area
MD, Johannes Gutenberg University
MD, PhD, Charité University
Postdoc, The Rockefeller University
Technology Development Fund Award
Mount Sinai Innovation
Cure Challenge Award
Kavli Frontiers in Science Fellow
The National Academy of Science
Chrissy Rossi Investigator
Seaver Autism Center
NIH Director’s New Innovator Award
NARSAD Young Investigator Award
German Research Foundation DFG
Hans-Hench Award 2005
German Society for Immunology, Germany
Summa cum lauden
Charité University Berlin
Keystone Scholar Travel Award
USA Research Scholarship
The German National Academic Foundation
German National Merit Foundation
Our research focuses on identifying the epigenetic basis of neurodegenerative and psychiatric disorders. We study how miRNAs and histone modifying enzymes contribute to the establishment and maintenance of neuronal identity and specialized functions. We are particularly interested in understanding the epigenetic mechanisms of cellular plasticity and its role in regulation of microglia-neuron communication. One of the major focuses of our research lies in the development of animal models of human neurological disease associated with abnormal function of epigenetic regulators of different types. Using pioneering technologies including cell type specific analysis of mRNAs, miRNAs and chromatin modifications in neurons in vivo, our research aims at understanding the mechanism of neurological disorders and at their potential treatment by targeting the neuronal epigenome.
Postdoctoral Fellow: Melanie von Schimmelmann
Research Personnel: Philip Feinberg
Postdoctoral Fellow: Pinar Ayata
PhD Student: Andrew Browne
Prep Student: Miriam Akeju
Volunteer: Silas Mann
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Schaefer during 2019 and/or 2020. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
- Neuroinflammation NewCo
Other activities: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership
- Eli Lilly
- Genentech, Inc.
- Neuroinflammation NewCo
- Pfizer Inc.
- The Rockefeller University
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