Photo of Alice Silva(Kamphorst)

Alice O Silva(Kamphorst), PhD Email Alice Silva(Kamphorst)

    • Position
    • ASSISTANT PROFESSOR | Oncological Sciences
    • Language
    • English

Alice O. Kamphorst, PhD is an Assistant Professor of Oncological Sciences at the Precision Immunology Institute. She is also a member of the Cancer Immunology Research Program at the Tisch Cancer Institute.

The Kamphorst lab focuses on T cell differentiation with a specific interest on situations of chronic antigen stimulation, such as in cancer. The research program aims to determine how inflammation, costimulation and other factors in the microenvironment influence CD8 T cell differentiation, dysfunction and rescue by immunotherapy. We study the interplay of different signaling pathways with the PD-1 (programmed cell death-1) pathway. To address those questions the lab uses mouse models of chronic viral infection and tumor, as well as analysis of samples from cancer patients.

https://kamphorstlab.org/

Research Topics

Anti-Tumor Therapy, Immunology, Infectious Disease, Inflammation, Liver, Lymphocytes, T Cells, Translational Research, Viruses and Virology

Education

PhD, Rockefeller University

Postdoc, Emory University

Language

English