Adam A Margolin, PhD Email Adam Margolin
- DIRECTOR, ICAHN INSTITUTE FOR GENOMICS AND MULTISCALE BIOLOGY
- SENIOR ASSOCIATE DEAN FOR PRECISION MEDICINE
Dr. Margolin is a recognized leader in developing machine learning algorithms to analyze large-scale molecular datasets, to predict therapies specific for an individual patient, and to infer the key cellular processes that underlie cancer drug susceptibility and other clinically relevant phenotypes. He is a passionate advocate of highly collaborative team-based research, and has developed software systems to enable collaborative analysis for several of the largest national and international projects in cancer genomics, cancer immunotherapy, stem cell research, and pediatric diseases.
As Chair of the Department of Genetics and Genomic Sciences, Dr. Margolin oversees a vibrant enterprise that is ranked fourth nationally among medical schools in National Institutes of Health funding for genetics research. The Department’s research encompasses the basic mechanisms of genetic regulation, translational genomics research, and genomic medicine. Additionally, the Department operates an internationally-renowned medical genetics faculty practice and trains clinical fellows. As Director of the Icahn Institute for Genomics and Multiscale Biology, Dr. Margolin leads a world-class computational genomics Institute focused on integrating the digital universe of biomedical data to advance discovery and delivery of revolutionary treatments.
In his role as Senior Associate Dean for Precision Medicine, Dr. Margolin works closely with other senior leaders to accelerate Mount Sinai’s commanding Precision Medicine program. Precision medicine, a major component of the ISMMS Strategic Plan, presents an opportunity to revolutionize the delivery of health care by customizing disease diagnosis, treatment, and prevention to individual patient needs.
Before joining Mount Sinai, Dr. Margolin served as Director of Computational Biology and Professor of Biomedical Engineering with Oregon Health & Science University, where he led the University’s computational research and informatics software development programs. Prior to that, Dr. Margolin was the Director of Computational Biology at Sage Bionetworks in Seattle. He also worked at the Broad Institute of Harvard and the Massachusetts Institute of Technology, leading an effort to leverage large-scale cancer genomics datasets to infer genotype-specific therapeutics in human tumors.
Dr. Margolin earned his MS in Computer Science from the School of Engineering at the University of Pennsylvania, and his PhD in Biomedical Informatics from Columbia University.
MS, University of Pennsylvania
PhD, Columbia University
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr.Margolin did not report having any of the following types of financial relationships with industry during 2017 and/or 2018: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
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