Orthopaedic Research

The Leni & Peter W. May Department of Orthopaedics at the Icahn School of Medicine at Mount Sinai is dedicated to understanding health conditions spanning the field of Orthopaedics. Our research studies involve clinical, translational, and basic science studies on a wide variety of crucially important musculoskeletal disorders. For example, low back pain is the second most common cause of disability in US adults and is commonly associated with intervertebral disc degeneration. Tears of the rotator cuff and other tendons are also very common and can cause extremely painful and disabling conditions.

Our researchers are focused on discovering causes of painful orthopaedic diseases, and we use this information to develop novel treatments, devices, and procedures that can improve quality of life for patients. Our research staff is dedicated to understanding conditions spanning the field of Orthopaedics, including joint mechanics, spine diseases, and musculoskeletal injury. Current research interests of the Leni and Peter W. May Department of Orthopaedics Faculty include:

  • Understanding why tendon fatigue injuries are slow to heal
  • Designing safe and effective rehabilitation techniques for tendon repair
  • Developing strategies to improve tendon healing
  • Studying the biomechanical and biological alterations that make intervertebral disc degeneration painful
  • Developing minimally invasive strategies for biomechanical repair of intervertebral disc herniations
  • Understanding how diet and systemic diseases, like diabetes, affect spine health
  • Developing strategies to image and assess functional changes to injured peripheral nerves

Results from our studies are shared with physicians and medical professionals worldwide through publications in peer-reviewed medical journals and textbooks. Research funding is supported by the National Institutes of Health, and prestigious foundations including the AO Research Foundation, and the Orthopaedic Research and Education Foundation. Our faculty are widely recognized for their clinical care and research, and collaborate with clinical and research colleagues in related specialties to provide the most advanced and well-informed care to the patients of The Mount Sinai Hospital.

More information can be found by visiting the Orthopaedics Research Laboratory at Mount Sinai.