Acute epididymitis is an inflammation of the epididymis. This is a structure that surrounds and attaches to each testicle. It is shaped like a tube. The epididymis helps transport and store sperm cells.
Chronic epididymitis causes discomfort or pain in the epididymis. It can last for 3 months or longer. This type is less common.
This condition is most often caused by a bacterial infection. For example:
- Urinary tract infection
- Sexually transmitted diseases (STDs), such as chlamydia and gonorrhea
- Infection of the urethra—urethritis
- Infection of the prostate—prostatitis
Other causes include:
Only men can develop this condition. It affects men age 15-30 with sexually transmitted bacteria begin a common cause. It also affects men over 60 with urinary tract infections being a common cause.
Other factors that increase the risk of epididymitis include:
- Infection of the genitourinary tract—urethra, bladder, kidney, prostate, or testicle
- Narrowing of the urethra
- Use of a urethral catheter
- Infrequent emptying of the bladder
- Recent surgery or instrumentation of the genitourinary tract—especially prostate removal
- Birth defects of the genitourinary tract
- Unprotected sex
- Disease that affects the immune system
Children and newborns can get epididymitis.
Symptoms usually develop within 1 day. These include:
- Pain in the testicles
- Sudden redness or swelling of the scrotum
- Hardness, a lump, and/or soreness in the affected testicle
- Tenderness in the unaffected testicle
- Groin pain
- Inflammation of the urethra
- Pain during intercourse or ejaculation
- Pain and/or burning during urination
- Increased pain while having a bowel movement
- Lower abdominal discomfort
- Discharge from the penis
You will be asked about your symptoms and medical history. A physical exam will be done.
Your bodily fluids may be tested. This can be done with:
- Urine culture
- Culture or other test of discharge from penis
- Blood tests
Images may be taken of your scrotum. This can be done with ultrasound.
Treatment is essential to prevent the infection from worsening. Treatment may include:
- Bed rest—This keeps the testicles from moving and promotes healing. You may need bed rest until the swelling goes away.
- Antibiotics—You will be given antibiotics to treat a bacterial infection. Many cases of epididymitis are caused by sexually transmitted bacteria. Chlamydia is one of the most common. If you have an STD , your partner(s) will also need treatment.
- Oral anti-inflammatory medication—This includes drugs like ibuprofen to help reduce swelling.
- Scrotal elevation and support—You may need to wear an athletic supporter for several weeks.
- Warm baths—Taking baths can ease the pain and help relieve swelling.
- Surgery—This may be needed in severe cases that keep coming back.
The following steps can help decrease your risk:
- Practice safe sex. Protect yourself from STDs by using condoms .
- Empty your bladder as soon as you feel the need.
National Kidney Foundation
Urology Care Foundation
The Kidney Foundation of Canada
Acute epididymitis. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T114552/Acute-epididymitis. Accessed May 23, 2016. Accessed September 23, 2016.
Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines, 2010. MMWR. 2010;59(No. RR-12):1-110.
Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guide: 2006. MMWR. 2006;55. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/std/treatment/2006/rr5511.pdf. Accessed August 31, 2015.
Hori S, Sengupta A, et al. Long-term outcome of epididymectomy for the management of chronic epididymal pain. J Urol. 2009 Oct;182(4):1407-1412.
Santillanes G, Gausche-Hill M, et al. Are antibiotics necessary for pediatric epididymitis? Pediatr Emerg Care. 2011 Feb 19.
Last reviewed August 2015 by Mohei Abouzied, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.