Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)
Recruitment Status: Recruiting
Start Date: November 01, 2007
End Date: May 01, 2024
Inclusion Criteria:
1. Children and young adults diagnosed with one of the four cholestatic diseases from birth through 25 years old.
2. Siblings of participants with alpha-1-antitrypsin deficiency, who themselves have alpha-1-antitrypsin deficiency of liver disease.
3. Both genders, all races and ethnic groups
4. Participant meets the enrollment criteria for one of the four cholestatic liver diseases
Exclusion Criteria:
1. Inability to comply with the longitudinal follow-up described below, or
2. Failure of a family/patient to sign the informed consent document or the HIPAA medical record release form.