Genetic Testing to Understand and Address Renal Disease Disparities Across the United States
Study Phase: N/A
Recruitment Status: Recruiting
Start Date: July 06, 2020
End Date: July 15, 2022
Inclusion Criteria:
- African American/Black
- English Speaking
- Age 18-70 years
- Have diagnosis of hypertension Diagnosis of hypertension is defined by either:
- ICD10 diagnosis codes (i.e., I10; I11.x; I12.x; I13.x; I16.x) OR
- On active antihypertensive therapy for indication of hypertension OR
- Having systolic blood pressure of 140 mm Hg or greater in at least 2 of the last 3 consecutive recorded values in the EHR OR
- Having hypertension in the patient's medical record problem list
- Have been seen at ≥1 time in past year at a participating primary care site
- Either: 1) do not have diabetes and do not have CKD, or 2) have CKD; Participants with diabetes may be included as long as they also have CKD.
- CKD is defined by either: 1) ICD10 codes (i.e., N18.x; E08.22; E09.22; E10.22; E11.22;E13.22 (exclude Z94.0; N18.6; Z99.2)) OR
- 15 ≤ eGFR ≤ 60 ml/min for 2 time periods ≥ 3 months
- Diabetes is defined by:
- HbA1c ≥ 6.5 at least one time in the last year OR
- ICD10 diagnosis codes (see Appendix A) OR
- Having diabetes in the patient's medical record problem list
Exclusion Criteria:
- Have diabetes, but no CKD.
- Are currently on dialysis (ICD 10 codes N18.6, Z99.2 and Z94.0)
- Have ESRD (eGFR<15 ml/min)
- Have a left ventricular assist device (LVAD)
- Have a terminal illness
- Have patient-reported known pregnancy at time of enrollment
- Have had a liver, kidney, or bone marrow transplant
- Too cognitively impaired to provide informed consent and/or complete the study protocol
- Institutionalized or too ill to participate (i.e. incarcerated, psychiatric or nursing home facility)
- Plan to move out of the area within 6 months of enrollment
- Not a current patient seeing a provider who cares for their hypertension (i.e., family medicine, internal medicine, nephrology, HIV provider, cardiology, hypertension specialists) at a participating site
- Previously participated in the GUARDD pilot study OR have previously undergone APOL1 testing
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Conditions:
- Kidney Diseases