"Infusion Type Doesn’t Affect Brain Outcomes In Pediatric DKA" - Miriam E. Tucker
In children presenting to the emergency department with diabetic ketoacidosis (DKA), neither the rate of administration nor the sodium chloride content of intravenous fluids appears to significantly influence neurologic outcomes, new research suggests. In contrast, "in the current study, which was performed at specialized centers with specialized staff, DKA–related brain injury appears unlikely to have been caused by the composition or rate of intravenous therapy. These conclusions are likely to generate discussion and lead to revision of current recommendations," wrote Mark A. Sperling, MD, professional lecturer in the department of pediatrics in the division of endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai, in an accompanying editorial. "DKA remains the leading cause of complications, death, and excessive healthcare utilization and costs in patients with type 1 diabetes," he stresses.
- Mark A. Sperling, MD, Professional Lecturer, Department of Pediatrics, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai
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