NBC News - "After Tragedy, Who Bounces Back? Keys to Resiliency May Lie in Childhood"

 – June 2, 2013  –– 

Although research has identified genes that indicate a predisposition to resiliency or vulnerability to trauma, environmental influences at critical developmental periods, like infancy and early childhood, may also play a significant role. Neuroscientist Dr. Eric Nestler, Director of the Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai, believes environmental impact on genes partly explains why people respond differently to adversity. Nestler's lab has tested stress responses and epigenetic changes in mice. Their brains showed modifications to genes that control stress response. "The challenge is if you look at the people subjected to these horrendous life events," he said, "while most people do OK…we have no understanding of why the same inputs lead to such a disparate outcome. Presumably, that is driven by different genetics and different epigenetics." Learn more