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Yu-Feng Chan

  • ASSISTANT PROFESSOR Genetics and Genomic Sciences
  • ASSISTANT PROFESSOR Emergency Medicine
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  • American Board of Emergency Medicine

Clinical Focus


  • MD, New Jersey Medical School - Rutgers University

  • PhD, Icahn School of Medicine
    Clinical Research

  • Internship, Internal Medicine
    University Hospital (UMDNJ)

  • Residency, Emergency Medicine
    Long Island Jewish Medical Center


    Yu-Feng Yvonne Chan, MD, PhDc, is a board-certified Emergency Medicine physician with formal training in clinical research as well as experience in stroke clinical trials, pharmacogenetics, and patient education. Dr. Chan attended Rutgers-New Jersey Medical School (NJMS) in Newark and trained in Emergency Medicine at Albert Einstein Medical School and Long Island Jewish Medical Center. She returned to NJMS as an Emergency Medicine (EM) attending physician after residency. During her 7 years at University Hospital (UH), Dr. Chan served as the Associate then Research Director for the EM residency and medical student EM electives as well as the fieldwork site supervisor for the MD/MPH students. Dr. Chan received a $250,000 grant from the Health Care Foundation of NJ to establish a Stroke Education Center in the Emergency Department waiting room. She was also a co-investigator for UH’s CDC HIV Counseling, Testing, and Referral Services grant. In January, 2008, Dr. Chan took an EM faculty position at Icahn School of Medicine at Mount Sinai to pursue formal training in clinical research. After a two year NIH/National Institute of Neurological Disorders and Stroke (NINDS) T32 Post-doctoral Cerebrovascular Research Fellowship at Sinai, she was awarded the NIH Institutional KL2 Clinical and Translational Research Career Development PhD Candidate Award. The expected date of the receipt of her PhD in Clinical Research from the Mount Sinai Graduate School of Biological Sciences is September, 2014. Currently, Dr. Chan is the Principal Investigator of the NIH Clinical and Translational Science Award-funded gene association study ‘Pharmacogenetics of Clopidogrel in the Mount Sinai Biobank Cohort’. She is also a co-investigator of two NINDS clinical trials: the ‘Platelet-Oriented Inhibition in New TIA and minor ischemic stroke (POINT) Trial’ as well as the DESERVE trial. In addition, Dr. Chan is collaborating with the Institute of Personalized Medicine faculty on the CLIPMERGE (CLinical Implementation of Personalized Medicine through Electronic Health Records and Genomics) project. Research Interests: • Pharmacogenomics of acute stroke therapies • Stroke genomics • Personalized medicine • Stroke clinical trials • Stroke education Nationally, Dr. Chan was elected as Chair of the Society of Academic Emergency Medicine's Neurological Interest Group. She was an American College of Emergency Medicine representative for the NINDS Brain Attack Coalition Stroke Messaging Committee and a participant at the NIH Roundtable on Opportunities to advance Research on Neurological and Mental Health Emergencies. She is a member of the American Stroke Association Stroke Committees as well as the International Stroke Genetics Consortium (ISGC). In addition, she is an active writing group member of the American Heart Association Guidelines for CPR and Emergency Cardiovascular Care as well as the ISGC Protocols and Guidelines. Within the Mount Sinai system, Dr. Chan chaired the Stroke Arrivals Committee and serves as the Emergency Medicine liaison for the Comprehensive Stroke Center as well as the Stroke Emergency Medicine Combined Conference.


  • 2007 -
    Northern New Jersey Annual Volunteer Recognition Power to End Stroke Honoree
    American Heart Association/ American Stroke Association

  • 2003 -
    Semi-Finalist for UMDNJ Process Improvement and Innovation Award
    Stroke/Transient Ischemic Attack Disease Process Team

  • 2000 -
    Best Resident Researcher
    Department of Emergency Medicine


Dr. Chan's current research interests include Cerebrovascular and Cardiovascular genomics, Pharmacogenomics, Stroke clinical trials.


Chan YF, Sproule W, Ordonez E, Nagurka R. Medical Utilization of Kiosks.. Health Promotion Perspectives;.

Moskowitz A, Chan YF, Singhal A. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood.. In: Normobaric and Hyperbaric Oxygen Therapy for Ischemic Stroke and Other Conditions.. John Wiley & Sons, Ltd.; 2011.prettyprintppp. 159-177.

Chan YF, Jauch EC, Cucchiara B, Adeoye O, Meurer W, Brice J. Part 11: adult stroke. 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care 2010 Nov; 2(122): 818-28.

Chan YF, D'Onofrio G, Jauch E, Jagoda A. NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies. Jauch E, Jagoda A, Allen MH, Anglin D, Barsan WG, Berger RP, Bobrow BJ, Boudreaux ED, Bushnell C, Chan YF, Currier G, Eggly S, Ichord R, Larkin GL, Laskowitz D, Neumar RW, Newman-Toker DE, Quinn J, Shear K, Todd KH, Zatzick D; Roundtable External Participants and Roundtable Steering Committee and Federal Participants. . Ann Emergency Medicine 2010 Nov; 56(6): 551-64.

Chan YF, Alagappan K, Rella J, Bentley S, Soto-Greene M, Martin M. Interpreter services in the Emergency Department.. Journal of Emergency Medicine 2010 Feb; 38(2): 133-139.

Chan YF, Richardson L, Zaets S, Nagurka R. The Effectiveness of Stroke Education in the Emergency Department Waiting Room. . Journal of Stroke and Cerebrovascular Diseases. 2010; 19(3): 209-215.

Chan YF, Moskowitz A, Bruns J. Barriers to Telestroke Implementation: A Pilot Survey of Physician Attitudes and Beliefs. Stroke 2010; 41(4): 805-9.

Chan YF. SAEM Board Retires Stroke Policy Statement. . ACEP News. 2009 June; 28(6): 14.

Chan YF, Jagoda A. Transient ischemic attack overview: defining the challenges for improving outcomes.. Annals of Emergency Medicine. 2008 Aug; 52(2): 3-6.

Chan YF, Lavery R, Fox N, Kwon R, Zinzuwadia S. The effect of an educational video on Emergency Department patient stroke knowledge. . Journal of Emergency Medicine 2008; 34(2): 215-220.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Chan did not report having any of the following types of financial relationships with industry during 2013 and/or 2014: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at Patients may wish to ask their physician about the activities they perform for companies.

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