Dr. Gabbay serves as Chief of the Pediatric Mood and Anxiety Disorders Program and Associate Professor of Psychiatry and Neuroscience.
One of the nation's leading experts on pediatric mood disorders, Dr. Gabbay is also a renowned researcher with a focus on the neurological and immunological mechanisms that contribute to the development and maintenance of mood disorders in youth. At the Mount Sinai School of Medicine, she will develop and direct a research program investigating the neurobiology of mood and anxiety disorders in children and adolescents with emphasis on the dimensional investigation of specific symptoms such as anhedonia - the capacity to experience pleasure. The goal of the program is to utilize a multidisciplinary approach to enhance understanding of the disorders, which will lead to early identification, diagnostic refinements, and novel treatments. Her research efforts utilize an array of sophisticated, cutting-edge techniques, including functional magnetic resonance (MR) imaging, MR spectroscopy, immunological and genetic assays, and comprehensive clinical evaluations. She also investigates the efficacy and neurochemical effects of Omega-3 fatty acids (fish oils) in the treatment of adolescent depression and Tourette's disorder. Dr. Gabbay's research has been funded by the National Institutes of Health, the American Foundation for Suicide Prevention, the Tourette Syndrome Association, the Hope for Depression Research Foundation, and the National Association for Research on Schizophrenia and Depression.
Dr. Gabbay has received numerous awards and honors and has been published extensively in top-tier scientific journals.
Dr. Gabbay received her BMedSc in human sciences and her MD from Tel Aviv University in Israel. She completed a residency in general psychiatry at the Albert Einstein College of Medicine and a residency in child and adolescent psychiatry at the NYU School of Medicine, where she received the Resident Research Excellence Award and, in 2008, earned her MS in Translational Medicine Research.
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Child & Adolescent Psychiatry
Psychiatry, American Board of Psychiatry and Neurology
MD, Sackler School of Medicine
Albert Einstein College of Medicine
Residency, Child and Adolescent Psychiatry
New York University School of Medicine
The Neuroimmunology of Anhedonia
The purpose of this study is to investigate the possible biological causes of adolescent depression. In order to participate, subjects with depression must be between the ages of 12 and 18 and not currently be taking any psychotropic medication. The study consists of 2 visits:...
Neuroinflammation and Positive Valence System Deficits in Adolescents
The purpose of this study is to investigate adolescent reward processing. In order to participate, subjects with any psychiatric symptoms must be between the ages of 12 and 18 and not currently be taking any psychotropic medication. The study consists of 2 visits:
Ely BA, Xu J, Goodman WK, Lapidus KA, Gabbay V, Stern ER. Resting-state functional connectivity of the human habenula in healthy individuals: Associations with subclinical depression. Human brain mapping 2016 Mar;.
Bradley KA, Colcombe S, Henderson SE, Alonso CM, Milham MP, Gabbay V. Neural correlates of self-perceptions in adolescents with major depressive disorder. Developmental cognitive neuroscience 2016 Feb; 19.
Bradley KA, Mao X, Case JA, Kang G, Shungu DC, Gabbay V. Increased ventricular cerebrospinal fluid lactate in depressed adolescents. European psychiatry : the journal of the Association of European Psychiatrists 2016 Jan; 32.
Réus GZ, Jansen K, Titus S, Carvalho AF, Gabbay V, Quevedo J. Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: Evidences from animal and human studies. Journal of psychiatric research 2015 May;.
Bradley KA, Case JA, Khan O, Ricart T, Hanna A, Alonso CM, Gabbay V. The role of the kynurenine pathway in suicidality in adolescent major depressive disorder. Psychiatry research 2015 Apr;.
Gabbay V, Johnson AR, Alonso CM, Evans LK, Babb JS, Klein RG. Anhedonia, but not Irritability, Is Associated with Illness Severity Outcomes in Adolescent Major Depression. Journal of child and adolescent psychopharmacology 2015 Mar;.
Henderson SE, Vallejo AI, Ely BA, Kang G, Krain Roy A, Pine DS, Stern ER, Gabbay V. The neural correlates of emotional face-processing in adolescent depression: a dimensional approach focusing on anhedonia and illness severity. Psychiatry research 2014 Dec; 224(3).
Gabbay V, Ely BA, Li Q, Bangaru SD, Panzer AM, Alonso CM, Castellanos FX, Milham MP. Striatum-based circuitry of adolescent depression and anhedonia. Journal of the American Academy of Child and Adolescent Psychiatry 2013 Jun; 52(6).
Gabbay V, Babb JS, Klein RG, Panzer AM, Katz Y, Alonso CM, Petkova E, Wang J, Coffey BJ. A double-blind, placebo-controlled trial of ω-3 fatty acids in Tourette's disorder. Pediatrics 2012 Jun; 129(6).
Gabbay V, Mao X, Klein RG, Ely BA, Babb JS, Panzer AM, Alonso CM, Shungu DC. Anterior cingulate cortex γ-aminobutyric acid in depressed adolescents: relationship to anhedonia. Archives of general psychiatry 2012 Feb; 69(2).
Gabbay V, Klein RG, Katz Y, Mendoza S, Guttman LE, Alonso CM, Babb JS, Hirsch GS, Liebes L. The possible role of the kynurenine pathway in adolescent depression with melancholic features. Journal of child psychology and psychiatry, and allied disciplines 2010 Aug; 51(8).
Gabbay V, Liebes L, Katz Y, Liu S, Mendoza S, Babb JS, Klein RG, Gonen O. The kynurenine pathway in adolescent depression: preliminary findings from a proton MR spectroscopy study. Progress in neuro-psychopharmacology & biological psychiatry 2010 Feb; 34(1).
Gabbay V, Klein RG, Guttman LE, Babb JS, Alonso CM, Nishawala M, Katz Y, Gaite MR, Gonzalez CJ. A preliminary study of cytokines in suicidal and nonsuicidal adolescents with major depression. Journal of child and adolescent psychopharmacology 2009 Aug; 19(4).
Cullen KR, Gee DG, Klimes-Dougan B, Gabbay V, Hulvershorn L, Mueller BA, Camchong J, Bell CJ, Houri A, Kumra S, Lim KO, Castellanos FX, Milham MP. A preliminary study of functional connectivity in comorbid adolescent depression. Neuroscience letters 2009 Sep; 460(3).
Gabbay V, Coffey BJ, Guttman LE, Gottlieb L, Katz Y, Babb JS, Hamamoto MM, Gonzalez CJ. A cytokine study in children and adolescents with Tourette's disorder. Progress in neuro-psychopharmacology & biological psychiatry 2009 Aug; 33(6).
Gabbay V, Klein RG, Alonso CM, Babb JS, Nishawala M, De Jesus G, Hirsch GS, Hottinger-Blanc PM, Gonzalez CJ. Immune system dysregulation in adolescent major depressive disorder. Journal of affective disorders 2009 May; 115(1-2).
Gabbay V, Coffey BJ, Babb JS, Meyer L, Wachtel C, Anam S, Rabinovitz B. Pediatric autoimmune neuropsychiatric disorders associated with streptococcus: comparison of diagnosis and treatment in the community and at a specialty clinic. Pediatrics 2008 Aug; 122(2).
Gabbay V, Hess DA, Liu S, Babb JS, Klein RG, Gonen O. Lateralized caudate metabolic abnormalities in adolescent major depressive disorder: a proton MR spectroscopy study. The American journal of psychiatry 2007 Dec; 164(12).
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr. Gabbay has not yet completed reporting of Industry relationships.
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