- PROFESSOR Preventive Medicine
- PROFESSOR Medicine, Pulmonary, Critical Care and Sleep Medicine
- Since 2012 Dr. Lucchini has been Director of the Division of Occupational Medicine, Professor of Preventive Medicine, Director of the World Trade Center, Data Center and Director of NIOSH Education and Research Center for New York and New Jersey. He is also Associate Professor at the University of Brescia, Italy, Division of Occupational Medicine.
His research is focused on the health effects of neurotoxic chemicals and the biological mechanisms by which metals, pesticides, solvents, persistent organic pollutants, particulate matter in the environment and workplace cause injury in the human nervous system. Dr. Lucchini and his team have developed quantitative, state-of-the-art testing methodologies and advanced computerized instruments to assess an array of neurological functions including cognitive, motor, behavioral and sensory functions. He and his team have conducted studies in occupational groups, children and elderly with funding from the Italian National Fund, the European Union and NIEHS. Dr. Lucchini serves as principal investigator on a multi-institutional research project supported by an RO1 grant from NIEHS that is examining neurologic function in adolescents exposed to ambient manganese, and a case control study on genetic and environmental determinants of Parkinsonism in the province of Brescia, Italy. This investigation is an international consortium that includes the University of Brescia, University of California at Santa Cruz, Harvard School of Public Health, Columbia and Rutgers Universities.
New research topics in the New York Metropolitan Area are focused on the assessment of health outcomes in metal exposed welders, sandhog workers exposed to silica in tunnel construction, transportation workers and community exposed to diesel.
Borgese L, Salmistraro M, Gianoncelli A, Zacco A, Lucchini R, Zimmerman N, Pisani L, Siviero G, Depero LE, Bontempi E. Airborne particulate matter (PM) filter analysis and modeling by total reflection X-ray fluorescence (TXRF) and X-ray standing wave (XSW). Talanta 2012 Jan; 89: 99-104.
Lucchini RG, Guazzetti S, Zoni S, Donna F, Peter S, Zacco A, Salmistraro M, Bontempi E, Zimmerman NJ, Smith DR. Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission. Neurotoxicology 2012 Jan; 33(4): 687-96.
Lucchini RG, Riva MA, Sironi VA, Porro A. Torvis oculis: Occupational roots of behavioral neurotoxicology in the last two centuries and beyond. Neurotoxicology 2012 Jan; 33(4): 652-9.
Rentschler G, Covolo L, Ahmadi Haddad A, Lucchini RG, Zoni S, Broberg K. ATP13A2 (PARK9) polymorphisms influence the neurotoxic effects of manganese. Neurotoxicology 2012 Jan; 33(4): 697-702.
Bal-Price AK, Coecke S, Costa L, Crofton KM, Fritsche E, Goldberg A, Grandjean P, Lein PJ, Li A, Lucchini R, Mundy WR, Padilla S, Persico AM, Seiler AE, Kreysa J. Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation. ALTEX 2012; 29(2): 202-215.
Zoni S, Bonetti G, Lucchini R. Olfactory functions at the intersection between environmental exposure to manganese and Parkinsonism. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2012 Jun; 26(2-3): 179-82.
Lucchini RG, Dorman DC, Elder A, Veronesi B. Neurological impacts from inhalation of pollutants and the nose-brain connection. Neurotoxicology 2012 Dec; 33: 838-41.
Lucchini RG, Zoni S, Guazzetti S, Bontempi E, Micheletti S, Broberg K, Parrinello G, Smith DR. Inverse association of intellectual function with very low blood lead but not with manganese exposure in Italian adolescents. Environmental research 2012 Oct; 118.
Lucchini RG, Guazzetti S, Zoni S, Benedetti C, Fedrighi C, Peli M, Donna F, Bontempi E, Borgese L, Micheletti S, Ferri R, Marchetti S, Smith DR. Neurofunctional dopaminergic impairment in elderly after lifetime exposure to manganese. Neurotoxicology 2014 May;.
Solan S, Wallenstein S, Shapiro M, Teitelbaum SL, Stevenson L, Kochman A, Kaplan J, Dellenbaugh C, Kahn A, Biro FN, Crane M, Crowley L, Gabrilove J, Gonsalves L, Harrison D, Herbert R, Luft B, Markowitz SB, Moline J, Niu X, Sacks H, Shukla G, Udasin I, Lucchini RG, Boffetta P, Landrigan PJ. Cancer incidence in world trade center rescue and recovery workers, 2001-2008. Environmental health perspectives 2013 Jun; 121(6).
Freund A, Zuckerman N, Luo H, Hsu HH, Lucchini R. Diesel and silica monitoring at two sites following hurricane sandy. Journal of occupational and environmental hygiene 2014 Sep; 11(9).
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr. Lucchini did not report having any of the following types of financial relationships with industry during 2014 and/or 2015: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.
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